HLA allele
|
NPC cases (%)
|
Control subjects (%)
|
OR
|
95% CI
|
P
|
Ref
|
---|
Cw08
|
1.10 (3/272)
|
5.74 (17/296)
|
0.18
|
0.052 – 0.618
|
0.003
|
-
|
B14
|
0.74 (2/270)
|
7.43 (22/296)
|
0.09
|
0.021 – 0.388
|
0.0001
|
[22]
|
B14-Cw08
|
0.74 (2/270)
|
5.74 (17/296)
|
0.12
|
0.027 – 0.519
|
0.001
|
-
|
B51
|
11.11 (30/270)
|
5.74 (17/296)
|
1.98
|
1.067 – 3.679
|
0.025
|
[22]
|
B57
|
3.70 (10/270)
|
0.68(2/296)
|
5.48
|
1.190 – 25.224
|
0.017
|
[22]
|
B18
|
6.67 (18/270)
|
2.36 (7/296)
|
2.85
|
1.173 – 6.941
|
0.014
|
[24]
|
- N.B. 136 typing could be performed for the HLA-Cw locus in patient with NPC while only 135 could be performed in the same patients for the HLA-A and -B loci.