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Table 2 Most common (frequency > 2%) HLA-A/B, Cw/B and Cw/B two-locus haplotypes in TU

From: Associations between HLA Class I alleles and the prevalence of nasopharyngeal carcinoma (NPC) among Tunisians

Haplotype

TUNISIANS

Present in:*

 

HF

Dx100

D'

χ2

p

 

A/B

      

A*020101 B*5001

0.046

2.20

0.19

8.30

< 0.01

Caucasians, Hispanics, Tunisians1

A*020101 B*440201

0.037

2.90

0.74

38.00

< 0.001

Caucasians, Blacks

A*2301 B*5001

0.030

1.90

0.29

13.00

< 0.001

 

A*6802 B*1402

0.024

2.10

0.41

50.00

< 0.001

Mixed

A*020101 B*510101

0.024

1.50

0.33

8.70

< 0.05

Caucasians, Hispanics, Blacks, Tunisians1

Cw/B

      

Cw*0602 B*5001

0.122

9.10

0.84

120.00

< 0.001

Hispanics

Cw*0701 B*0801

0.047

3.80

0.69

65.00

< 0.001

Caucasians, Hispanics, Blacks, Tunisians1

Cw*0501 B*4402

0.041

3.90

0.87

22.00

< 0.001

Caucasians, Hispanics, Blacks, Tunisians1

Cw*0802 B*1402

0.037

3.40

0.66

120.00

< 0.001

Caucasians, Hispanics, Blacks, Tunisians1

Cw*0602 B*4501

0.034

2.40

0.65

22.00

< 0.001

Black

Cw*0702 B*070201

0.034

3.10

0.80

140.00

< 0.001

Caucasians, Blacks, Orientals

Cw*1502 B*510101

0.034

3.20

1.00

180.00

< 0.001

Caucasians, Hispanics, Tunisians1

Cw*0701 B*4901

0.027

2.30

0.99

54.00

< 0.001

Hispanics, Blacks, Tunisians1

Cw*0202 B*440301

0.027

2.20

0.33

32.00

< 0.001

 

Cw*1601 B*440301

0.027

2.40

0.58

59.00

< 0.001

Caucasians, Hispanics, Tunisians1

Cw*1202 B*520101

0.024

2.30

1.00

30.00

< 0.001

Hispanics, Orientals, Tunisians1

Cw*1701,03 B*4102

0.020

1.90

1.00

110.00

< 0.001

Very common

Cw*040101 B*3501

0.020

1.70

0.70

28.00

< 0.001

Caucasians, Hispanics, Blacks, Tunisians1

Cw*040101 B*5301

0.020

1.70

0.81

33.00

< 0.001

Hispanics, Blacks

Cw*120301 B*3801

0.020

1.90

1.00

130.00

< 0.001

Caucasians, Hispanic, Tunisians1

A/Cw

      

A*020101 Cw*0602

0.063

2.50

0.19

7.80

< 0.01

 

A*2301 Cw*0602

0.036

1.90

0.31

7.70

< 0.01

 

A*030101 Cw*0602

0.035

2.00

0.38

11.00

< 0.001

 

A*010101 Cw*040101

0.034

2.30

0.30

18.00

< 0.001

Blacks

A*020101 Cw*0501

0.033

2.50

0.62

28.00

< 0.001

 
  1. In bold: haplotypes shared with ME. Other haplotypes (in italics) are shared but were not in linkage (p = ns) or were present at low frequency (< 1.5%) in ME.
  2. HF: haplotype frequency; SD: standard deviation; Dx100: linkage disequilibrium multiplied by 100; D': relative linkage disequilibrium; ChiSQ: chi-square values
  3. * According to the allele frequency worldwide population database [42,43].
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Journal of Translational Medicine

ISSN: 1479-5876

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