Skip to main content

Table 2 Most common (frequency > 2%) HLA-A/B, Cw/B and Cw/B two-locus haplotypes in TU

From: Associations between HLA Class I alleles and the prevalence of nasopharyngeal carcinoma (NPC) among Tunisians

Haplotype TUNISIANS Present in:*
  HF Dx100 D' χ2 p  
A/B       
A*020101 B*5001 0.046 2.20 0.19 8.30 < 0.01 Caucasians, Hispanics, Tunisians1
A*020101 B*440201 0.037 2.90 0.74 38.00 < 0.001 Caucasians, Blacks
A*2301 B*5001 0.030 1.90 0.29 13.00 < 0.001  
A*6802 B*1402 0.024 2.10 0.41 50.00 < 0.001 Mixed
A*020101 B*510101 0.024 1.50 0.33 8.70 < 0.05 Caucasians, Hispanics, Blacks, Tunisians1
Cw/B       
Cw*0602 B*5001 0.122 9.10 0.84 120.00 < 0.001 Hispanics
Cw*0701 B*0801 0.047 3.80 0.69 65.00 < 0.001 Caucasians, Hispanics, Blacks, Tunisians1
Cw*0501 B*4402 0.041 3.90 0.87 22.00 < 0.001 Caucasians, Hispanics, Blacks, Tunisians1
Cw*0802 B*1402 0.037 3.40 0.66 120.00 < 0.001 Caucasians, Hispanics, Blacks, Tunisians1
Cw*0602 B*4501 0.034 2.40 0.65 22.00 < 0.001 Black
Cw*0702 B*070201 0.034 3.10 0.80 140.00 < 0.001 Caucasians, Blacks, Orientals
Cw*1502 B*510101 0.034 3.20 1.00 180.00 < 0.001 Caucasians, Hispanics, Tunisians1
Cw*0701 B*4901 0.027 2.30 0.99 54.00 < 0.001 Hispanics, Blacks, Tunisians1
Cw*0202 B*440301 0.027 2.20 0.33 32.00 < 0.001  
Cw*1601 B*440301 0.027 2.40 0.58 59.00 < 0.001 Caucasians, Hispanics, Tunisians1
Cw*1202 B*520101 0.024 2.30 1.00 30.00 < 0.001 Hispanics, Orientals, Tunisians1
Cw*1701,03 B*4102 0.020 1.90 1.00 110.00 < 0.001 Very common
Cw*040101 B*3501 0.020 1.70 0.70 28.00 < 0.001 Caucasians, Hispanics, Blacks, Tunisians1
Cw*040101 B*5301 0.020 1.70 0.81 33.00 < 0.001 Hispanics, Blacks
Cw*120301 B*3801 0.020 1.90 1.00 130.00 < 0.001 Caucasians, Hispanic, Tunisians1
A/Cw       
A*020101 Cw*0602 0.063 2.50 0.19 7.80 < 0.01  
A*2301 Cw*0602 0.036 1.90 0.31 7.70 < 0.01  
A*030101 Cw*0602 0.035 2.00 0.38 11.00 < 0.001  
A*010101 Cw*040101 0.034 2.30 0.30 18.00 < 0.001 Blacks
A*020101 Cw*0501 0.033 2.50 0.62 28.00 < 0.001  
  1. In bold: haplotypes shared with ME. Other haplotypes (in italics) are shared but were not in linkage (p = ns) or were present at low frequency (< 1.5%) in ME.
  2. HF: haplotype frequency; SD: standard deviation; Dx100: linkage disequilibrium multiplied by 100; D': relative linkage disequilibrium; ChiSQ: chi-square values
  3. * According to the allele frequency worldwide population database [42,43].