Figure 1

All mice that received PBS (crosses) developed tumors by day 14 post-immunization. A single immunization against a mixture of TRP2:181–188 and modified p53:232–240 in VM (triangles) rendered all mice tumor-free by 21 days post-immunization. A single administration of TRP2:181–188 alone alone (diamonds) in VM rendered 2/5 mice tumor-free by day 16 post-immunization. A single administration of modified p53:232–240 in VM (squares) delayed tumor development in one mouse, but by day 21 post-immunization, all mice in this group were tumor bearing. In the interval between 25 and 27 days post-immunization, two mice in this group became tumor-free.