Table 9 Proportion of Peripheral Blood CD4+ T Cells From 20 Healthy CMV-Seropositive Subjects Producing Intracellular IFN-γ Following Stimulation With a Library of 138 CMV pp65 15-mer Peptides and Each of 14 subpools of 10 Peptides*
From: CMV pp65 and IE-1 T cell epitopes recognized by healthy subjects
|  | CD4+ T Cells Producing Intracellular IFN-γ in Each Donor (%) | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Â | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 |
Library | 0.16 | 0.06 | 0.00 | 0.06 | 0.11 | 0.76 | 0.11 | 0.65 | 0.08 | 0.21 | 3.33 | 0.18 | 0.20 | 1.34 | 0.23 | 0.02 | 0.15 | 0.03 | 0.04 | 0.01 |
Subpool | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
1 | 0.01 | 0.01 | 0.02 | 0.01 | 0.02 | 0.03 | 0.00 | 0.03 | 0.02 | 0.01 | 0.03 | 0.05 | 0.08 | 0.05 | 0.04 | 0.00 | 0.02 | 0.01 | 0.01 | 0.04 |
2 | 0.05 | 0.09 | 0.01 | 0.03 | 0.05 | 0.05 | 0.02 | 0.04 | 0.02 | 0.01 | 0.03 | 0.06 | 0.02 | 0.06 | 0.03 | 0.02 | 0.03 | 0.04 | 0.01 | 0.03 |
3 | 0.03 | 0.02 | 0.01 | 0.01 | 0.03 | 0.03 | 0.04 | 0.05 | 0.05 | 0.03 | 0.03 | 0.06 | 0.03 | 0.06 | 0.06 | 0.00 | 0.03 | 0.02 | 0.04 | 0.02 |
4 | 0.01 | 0.06 | 0.02 | 0.01 | 0.03 | 0.06 | 0.00 | 0.09 | 0.01 | 0.02 | 0.04 | 0.04 | 0.01 | 0.03 | 0.04 | 0.01 | 0.01 | 0.02 | 0.02 | 0.00 |
5 | 0.02 | 0.04 | 0.01 | 0.01 | 0.02 | 0.02 | 0.00 | 0.04 | 0.04 | 0.01 | 0.04 | 0.05 | 0.02 | 0.07 | 0.02 | 0.02 | 0.01 | 0.00 | 0.01 | 0.01 |
6 | 0.02 | 0.04 | 0.01 | 0.04 | 0.01 | 0.03 | 0.01 | 0.45 | 0.04 | 0.11 | 0.02 | 0.18 | 0.02 | 0.01 | 0.02 | 0.02 | 0.01 | 0.04 | 0.01 | 0.03 |
7 | 0.01 | 0.05 | 0.04 | 0.01 | 0.01 | 0.02 | 0.02 | 0.03 | 0.01 | 0.07 | 0.02 | 0.06 | 0.05 | 0.04 | 0.07 | 0.02 | 0.02 | 0.07 | 0.02 | 0.01 |
8 | 0.04 | 0.04 | 0.01 | 0.03 | 0.02 | 0.09 | 0.05 | 0.12 | 0.01 | 0.01 | 0.04 | 0.08 | 0.00 | 0.07 | 0.05 | 0.02 | 0.01 | 0.03 | 0.01 | 0.03 |
9 | 0.06 | 0.13 | 0.03 | 0.03 | 0.03 | 0.05 | 0.05 | 0.04 | 0.03 | 0.01 | 0.05 | 0.05 | 0.01 | 0.06 | 0.02 | 0.02 | 0.01 | 0.03 | 0.02 | 0.09 |
10 | 0.14 | 0.02 | 0.00 | 0.03 | 0.05 | 0.56 | 0.00 | 0.10 | 0.05 | 0.04 | 2.76 | 0.08 | 0.01 | 0.96 | 0.03 | 0.02 | 0.02 | 0.01 | 0.02 | 0.00 |
11 | 0.03 | 0.02 | 0.00 | 0.00 | 0.02 | 0.15 | 0.00 | 0.08 | 0.01 | 0.01 | 0.06 | 0.13 | 0.01 | 0.07 | 0.01 | 0.01 | 0.01 | 0.01 | 0.00 | 0.01 |
12 | 0.04 | 0.03 | 0.01 | 0.00 | 0.02 | 0.04 | 0.01 | 0.05 | 0.04 | 0.01 | 0.01 | 0.04 | 0.00 | 0.06 | 0.03 | 0.02 | 0.02 | 0.01 | 0.01 | 0.05 |
13 | 0.02 | 0.03 | 0.02 | 0.03 | 0.03 | 0.27 | 0.00 | 0.13 | 0.07 | 0.07 | 0.05 | 0.12 | 0.14 | 0.42 | 0.13 | 0.01 | 0.12 | 0.02 | 0.01 | 0.00 |
14 | 0.03 | 0.06 | 0.02 | 0.01 | 0.02 | 0.09 | 0.00 | 0.11 | 0.07 | 0.01 | 0.03 | 0.08 | 0.01 | 0.09 | 0.02 | 0.01 | 0.01 | 0.01 | 0.02 | 0.00 |