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Table 8 Individual IE-1 Epitopes that Induced Intracellular IFN-γ Production by CD8+ T Cells, the HLA Type of Donors With Reactive CD8+ T Cells, and The HLA Antigen Restriction of Each Epitope.

From: CMV pp65 and IE-1 T cell epitopes recognized by healthy subjects

Epitope

Donor

HLA-A*

HLA-B*

HLA-C*

HLA Antigen Restriction

Published Antigen Restriction

IE-187–95

05

11, 68

44, 45

05, 06

  
 

10

0301, 68

53, 58

04, 06

  
 

11

26, 74

15, 5802

0602, 1601

C*0602

 

IE-1198–206

15

0201, 30

18, 44

0501

†

IE-1199–207 B*18 [22]

IE-1300–308

06

26, 30

35, 57

04, 18

No cells available

IE-1297–304 A*0201 [27]

IE-1305–313

07

01, 0201

07, 35

04, 07

C*0702

 

IE-1308–316

02

24, 32

07, 40

02, 07

C*07

IE-1309–317 B*0702 [9]

 

07

01, 0201

07, 35

04, 07

  

IE-1312–320

07

01, 0201

07, 35

04, 07

C*07

 

IE-1319–327

05

11, 68

44, 45

05, 06

A*68

IE-1316–324 A*0201 [19]

IE-1378–386

15

0201, 30

18, 44

0501, 0501

†

IE-1379–387 B*18 [22]

  1. † Cells from donor 15 did not expand when stimulated with IE-1198–206 and IE-1378–386.
  2. The HLA antigen restrictions identified are shown in bold.