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Table 8 Individual IE-1 Epitopes that Induced Intracellular IFN-γ Production by CD8+ T Cells, the HLA Type of Donors With Reactive CD8+ T Cells, and The HLA Antigen Restriction of Each Epitope.

From: CMV pp65 and IE-1 T cell epitopes recognized by healthy subjects

Epitope Donor HLA-A* HLA-B* HLA-C* HLA Antigen Restriction Published Antigen Restriction
IE-187–95 05 11, 68 44, 45 05, 06   
  10 0301, 68 53, 58 04, 06   
  11 26, 74 15, 5802 0602, 1601 C*0602  
IE-1198–206 15 0201, 30 18, 44 0501 IE-1199–207 B*18 [22]
IE-1300–308 06 26, 30 35, 57 04, 18 No cells available IE-1297–304 A*0201 [27]
IE-1305–313 07 01, 0201 07, 35 04, 07 C*0702  
IE-1308–316 02 24, 32 07, 40 02, 07 C*07 IE-1309–317 B*0702 [9]
  07 01, 0201 07, 35 04, 07   
IE-1312–320 07 01, 0201 07, 35 04, 07 C*07  
IE-1319–327 05 11, 68 44, 45 05, 06 A*68 IE-1316–324 A*0201 [19]
IE-1378–386 15 0201, 30 18, 44 0501, 0501 IE-1379–387 B*18 [22]
  1. † Cells from donor 15 did not expand when stimulated with IE-1198–206 and IE-1378–386.
  2. The HLA antigen restrictions identified are shown in bold.