Table 6 Individual pp65 Epitopes that Induced Intracellular IFN-γ Production by CD8+ T Cells, the HLA Type of Donors With Reactive CD8+ T Cells, and HLA Antigen Restrictions of Each Epitope
From: CMV pp65 and IE-1 T cell epitopes recognized by healthy subjects
Epitope(s) | Donor | HLA-A* | HLA-B* | HLA-C* | HLA Antigen Restriction | Published Antigen Restriction |
|---|---|---|---|---|---|---|
pp65123–131 | 19 | 03, 29 | 35, 44 | 04, 1601 | B*35 | pp65123–131 B*3501 [20] |
pp65188–196 | 05 | 11, 68 | 44, 45 | 05, 06 | No cells available | pp65186–196 A*6801/2 [21] |
pp65417–425 and pp65418–426 | 03 | 01, 31 | 07, 27 | 0202, 0702 | No cells available |  |
|  | 07 | 01, 0201 | 07, 35 | 04, 07 | No cells available | pp65417–426 B*0702 [8,19] |
| Â | 14 | 010101, 2601 | 070201, 3801 | 070201, 120301 | HLA-B*07 | Â |
pp65 495–503 | 13 | 0201, 0201 | 15, 18 | 03, 07 | Not tested | pp65495–503 A*0201 [13,30] |