Figure 4

Orthotopic (bone) bioassay in rats – Quantitative analysis of Tomography Data. Volume (A): only CS-Platelet, rhBMP2, and the External control showed a statistically significant difference from the negative control (p < 0.001). Surface area (B): only CS-Platelet, rhBMP2, and the External control showed a statistically significant difference from the negative control (p < 0.001). Density (C): all treatment groups showed a density of the regenerated bone statistically different from the density of the bone normally present in an area of 8 mm of the calvaria (External control)(p < 0.001).