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Table 4 Thymocyte Repopulation of SCID-hu Thy/Liv Grafts

From: The thrombopoietin receptor, c-Mpl, is a selective surface marker for human hematopoietic stem cells

HLA+ Donor Cell Transplant

Non-injected Control

CD34+CD38--/dimc-mpl--

CD34+CD38--/dimc-mpl+

No. Mice Engrafted

NA

4/7

3/4

% Donor CD2+

2.66

2.80 (3.27)

6.83 (4.48)

% Donor CD4+8+

0.82

0.48 (0.47)

0.92 (0.64)

% Donor CD4+8-

9.84

30.7 (28.9)

54.1 (35.4)

% Donor CD4-8+

5.17

18.1 (14.3)

29.2 (19.4)

  1. HLA, human leukocyte antigen; SCID-hu Thy/Liv, scid/scid mouse with human thymus/liver implants