Skip to main content

Table 1 Summary of the clinical data of three patients

From: Differential expression profiling between the relative normal and dystrophic muscle tissues from the same LGMD patient

Physical and clinical examination

Clinical symptoms or indications

Physical development

Normal

Psychological development

Normal

Age onset

Two sisters in the second decade, the oldest in the third decade

First symptoms

Difficulty in climbing stairs and standing up from chair

Pattern of muscle involvement

Lower and upper limb-girdle muscle

Clinical course

Slow

Pseudohypertrophy of calf

Transient calf hypertrophy at early stage

cardiomyopathy

No

Serum creatine kinase (SCK)

Very high, approximately 10 times than normal

EMG

Myopathic damage

Muscle biopsy

Typical muscle dystrophic change