From: In situ analysis of FOXP3+ regulatory T cells in human colorectal cancer
 | n | FOXP3/HPF ± SD | P value |
---|---|---|---|
Healthy controls | 12 | 0.6 ± 0.3 |  |
   Mean age 64.6 years, 5 female, 7 male |  |  |  |
 |  |  | < 0.01 |
CRC | 40 | 12.9 ± 9.1 |  |
   Mean age 62.1 years, 21 female, 19 male |  |  |  |
Stromal | 40 | 10.8 ± 8.4 | < 0.01 |
Epithelial | 40 | 2.0 ± 2.2 |  |
Limited (UICC I+II) | 21 | 17.8 ± 10.6 | 0.04 |
Metastatic (UICC III+IV) | 19 | 9.9 ± 6.1 |  |
Positive T cell response | 11 | 9.6 ± 7.3 | 0.16 |
Negative T cell response | 29 | 14.1 ± 9.5 |  |