Table 2 Invasive Hemodynamics
From: Decreased wheel-running activity in hamsters post myocardial infarction
Isoprenaline, μg/kg/min | ||||
|---|---|---|---|---|
Baseline | 0.03 | 0.1 | 0.3 | |
Heart rate, bpm | ||||
Sham | 441 ± 70 | 455 ± 79 | 451 ± 77 | 431 ± 87 |
MI < 15% | 389 ± 45 | 423 ± 38 | 427 ± 50 | 410 ± 54 |
MI > 15% | 376 ± 53 * | 390 ± 46 | 387 ± 49 | 369 ± 67 |
LVPmax, mmHg | ||||
Sham | 117.1 ± 12.1 | 113.4 ± 13.4 | 118.0 ± 11.0 | 118.8 ± 12.1 |
MI < 15% | 108.8 ± 15.1 | 107.6 ± 16.2 | 108.2 ± 18.0 | 110.7 ± 18.1 |
MI > 15% | 102.0 ± 15.4 | 102.2 ± 11.4 | 103.1 ± 13.4 | 99.1 ± 9.3 * |
LVEDP, mmHg | ||||
Sham | 5.0 ± 3.2 | 4.6 ± 3.8 | 5.1 ± 3.4 | 8.6 ± 4.0 |
MI < 15% | 9.2 ± 6.9 | 9.1 ± 7.3 | 10.4 ± 8.4 | 13.3 ± 8.5 |
MI > 15% | 14.0 ± 6.2 * | 15.5 ± 6.9 * | 16.9 ± 7.9 * | 18.4 ± 8.8 * |
dP/dtmax, mmHg/s | ||||
Sham | 7795 ± 2150 | 7992 ± 2110 | 8692 ± 2283 | 8220 ± 1560 |
MI < 15% | 6365 ± 1458 | 6807 ± 1802 | 7319 ± 2184 | 7554 ± 2406 |
MI > 15% | 5010 ± 1171 * | 5137 ± 1626 * | 5234 ± 1466 *# | 5091 ± 1490 *# |
dP/dtmin, mmHg/s | ||||
Sham | 5954 ± 1863 | 5870 ± 1506 | 6153 ± 1498 | 6002 ± 1676 |
MI < 15% | 4793 ± 1530 | 4878 ± 1360 | 5028 ± 1642 | 4887 ± 1187 |
MI > 15% | 3851 ± 1041 * | 3876 ± 1130 * | 3881 ± 1012 * | 3667 ± 848 * |
τ, ms | ||||
Sham | 14.1 ± 8.0 | 11.9 ± 6.0 | 12.6 ± 6.4 | 12.2 ± 5.1 |
MI < 15% | 15.7 ± 7.4 | 13.7 ± 7.4 | 12.1 ± 5.4 | 11.3 ± 3.8 |
MI > 15% | 17.9 ± 7.2 | 18.4 ± 8.4 | 17.5 ± 7.5 | 15.7 ± 4.9 |