Figure 1From: Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatmentProposed model of how IL-1 indirectly alters tumor growth and metastatic potential in vivo. In the tumor microenvironment IL-1 has local effects on host infiltrating cells that result in production of proangiogenic and prometastatic mediators.Back to article page