Distribution of killer cell immunoglobulin-like receptors genes in the Italian Caucasian population

Bontadini, A; Testi, M; Cuccia, MC; Martinetti, M; Carcassi, C; Chiesa, A; Cosentini, E; Dametto, E; Frison, S; Iannone, AM; Lombardo, C; Malagoli, A; Mariani, M; Mariotti, L; Mascaretti, L; Mele, L; Miotti, V; Nesci, S; Ozzella, G; Piancatelli, D; Romeo, G; Tagliaferri, C; Vatta, S; Andreani, M; Conte, R

doi:10.1186/1479-5876-4-44

Journal of Translational Medicine

Table 2 Linkage disequilibrium values of KIR associations.

From: Distribution of killer cell immunoglobulin-like receptors genes in the Italian Caucasian population

		2DL2	2DL3	2DL5A	2DL5B	2DS1	2DS2	2DS3	2DS4* 001-002	2DS4* 003	2DS5	3DL1	3DS1
2	Δ	-0.004	0.097	0.025	0.019	0.01	0.004	0.036	0.03	0.001	0.006	0.031	0.003
D	R	-0.055	0.69	0.597	0.586	0.241	0.055	0.924	0.761	0.011	0.193	0.201	0.064
L	H	0.246	0.623	0.168	0.14	0.15	0.246	0.18	0.117	0.539	0.115	0.685	0.159
1	P		< 0.0001					< 0.05
2	Δ		-0.137	0.014	0.101	0.013	0.205	0.099	0.012	-0.031	0.003	-0.005	0.025
D	R		-1.186	0.106	0.990	0.096	0.944	0.811	0.1	0.295	0.026	0.087	0.196
L	H		0.071	0.07	0.149	0.077	0.304	0.156	0.071	0.181	0.05	0.252	0.087
2	P		< 0.0001		< 0.0001		< 0.0001	< 0.0001
2	Δ			0.001	-0.096	0.001	-0.115	-0.086	-0.022	0.025	-0.016	0.007	-0.028
D	R			0.022	-1.774	0.012	-1	-1.333	-0.347	0.120	-0.301	0.054	-0.407
L	H			0.12	0.005	0.135	0.092	0.032	0.1	0.471	0.084	0.549	0.102
3	P				< 0.0001		< 0.001	< 0.001
2	Δ				0.02	0.135	0.022	0.04	-0.05	-0.052	0.108	-0.051	0.133
D	R				0.162	0.886	0.167	0.269	-0.341	-0.835	0.887	-1.35	0.863
L	H				0.047	0.171	0.078	0.071	-0.016	0.069	0.135	0.096	0.168
5A	P					< 0.0001		< 0.001	< 0.0001	< 0.05
2	Δ					0.019	0.104	0.119	-0.01	-0.022	0.01	-0.035	0.018
D	R					0.162	1.022	0.969	-0.078	-0.445	0.071	-1.157	0.147
L	H					0.050.	0.152	0.146	0.02	0.08	0.032	0.1	0.048
5B	P						< 0.0001	< 0.0001
2	Δ						0.021	0.028	-0.05	-0.08	0.115	-0.047	0.127
D	R						0.156	0.195	-0.348	-1.212	0.962	-1.18	0.839
S	H						0.085	0.064	0.012	0.056	0.146	0.119	0.167
1	P							< 0.05	< 0.0001	< 0.05	< 0.0001		< 0.0001
2	Δ							0.106	0.016	-0.02	0.01	-0.005	0.025
D	R							0.868	0.132	0.185	0.103	-0.087	0.196
S	H							0.163
2	P							< 0.0001	0.075	0.192	0.058	0.252	0.087
2	Δ								-0.011	-0.032	0.003	-0.051	0.04
D	R								-0.076	-0.537	0.028	-1.425	0.275
S	H								0.022	0.09	0.031	0.096	0.075
3	P												< 0.001
2	Δ									-0.107	-0.039	0.0003	-0.039
D	R									-1.811	-0.321	0.009	-0.271
S	H									0.019	0.011	0.155	-0.003
4001 002	P									< 0.0001	< 0.01		< 0.05
2	Δ										-0.061	0.108	-0.07
D	R										-1.24	0.804	-1.108
S	H										0.041	0.661	0.063
4*003	P										< 0.05	< 0.000	< 0.05
2	Δ											-0.056	0.105
D	R											-1.876	0.862
S	H											0.068	0.135
5	P											< 0.05	< 0.0001
3	Δ												-0.076
D	R												-2.01
L	H												0.085
1	P												< 0.05

Δ = linkage disequilibrium parameters;R = relative linkage disequilibrium;H = estimated two locus haplotype frequency;P = p value

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ISSN: 1479-5876

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