Skip to main content

Table 5 Comparison of the Levels of 80 Soluble Factors in Heat Inactivated Serum and Heat Inactivated Recalcified Plasma

From: Comparison of proteomic profiles of serum, plasma, and modified media supplements used for cell culture and expansion

Factor Heat Inactivated Serum Heat Inactivated Recalcified Plasma P*
ACRP-30 (microg/mL) 15.9 ± 10.5 9.0 ± 5.8 0.000209
Amphiregulin (pg/mL) 7 ± 11 3 ± 5 N.S.
ANG-2 (pg/mL) 0 ± 0 0 ± 0 N.S.
Apo A-1 (microg/mL) 89.0 ± 16.6 70.0 ± 17.3 0.000433
ApoB-100 (microg/mL) 637 ± 147 544 ± 98 0.00831
A-SAA (microg/mL) 14.7 ± 4.80 11.4 ± 4.12 0.00228
BDNF (ng/mL) 7.23 ± 3.04 4.17 ± 1.54 N.S.
CD14 (pg/mL) 998 ± 2,439 9,922 ± 11,223 N.S.
CD40L (pg/mL) 48 ± 81 70 ± 63 N.S.
CNTF (pg/mL) 0 ± 0 0 ± 0 N.S.
CRP (microg/mL) 3.52 ± 0.84 2.33 ± 4.71 N.S.
ENA-78 (pg/mL) 637 ± 392 343 ± 122 N.S.
Eotaxin (pg/mL) 16 ± 26 25 ± 14 N.S.
Eotaxin2 (ng/mL) 1.66 ± 1.24 3.13 ± 2.33 0.000712
E-Selectin (ng/mL) 73.1 ± 16.7 70.0 ± 15.0 N.S.
Exodus 2 (pg/mL) 53 ± 21 106 ± 55 0.00976
FGF Basic (pg/mL) 218 ± 175 160 ± 219 N.S.
Fibrinogen (ng/mL) 174 ± 44.2 217 ± 76.7 N.S.
G-CSF (pg/mL) 29 ± 22 41 ± 19 N.S.
GM-CSF (pg/mL) 555 ± 267 623 ± 311 N.S.
GRO-alpha (pg/mL) 67 ± 61 36 ± 12 N.S.
HGF (pg/mL) 206 ± 124 224 ± 43 N.S.
HGH (pg/mL) 164 ± 148 159 ± 159 N.S.
I-309 (pg/mL) 27 ± 64 21 ± 38 N.S.
ICAM-1 (ng/mL) 145 ± 44.3 183 ± 48.7 0.00518
IFN-α (pg/mL) 1 ± 1.3 0.8 ± 1.3 N.S.
IFN-γ (pg/mL) 3 ± 9 3 ± 9 N.S.
IL-11 (pg/mL) 0 ± 0 0 ± 0 N.S.
IL-12p40 (pg/mL) 7 ± 15 6 ± 10 N.S.
IL-16 (pg/mL) 62 ± 19 66 ± 21 N.S.
IL-1α (pg/mL) 12 ± 26 11 ± 25 N.S.
IL-1Ra (pg/mL) 183 ± 328 150 ± 283 N.S.
IL-2 (pg/mL) 22 ± 32 21 ± 27 N.S.
IL-2R (ng/mL) 1.21 ± 0.67 1.49 ± 0.78 N.S.
IL-2Rγ (pg/mL) 0 ± 0 0 ± 0 N.S.
IL-6 (pg/mL) 7 ± 13 7 ± 12 N.S.
IL-6R (pg/mL) 30 ± 13 40 ± 10 0.00451
IL-7 (pg/mL) 5 ± 6 0.9 ± 2.6 N.S.
IL-8 (pg/mL) 7 ± 7 6 ± 9 N.S.
IL-9 (pg/mL) 771 ± 1,457 608 ± 1,259 N.S.
IP-10 (pg/mL) 128 ± 77 141 ± 55 N.S.
ITAC (pg/mL) 8 ± 10 8 ± 6 N.S.
KGF (pg/mL) 34 ± 17 26 ± 12 N.S.
LEPTIN (ng/mL) 2.15 ± 3.04 2.56 ± 3.06 N.S.
L-Selectin (microg/mL) 1.16 ± 0.32 1.06 ± 0.26 N.S.
Lymphotactin (pg/mL) 94 ± 107 86 ± 94 N.S.
MCP-1 (pg/mL) 456 ± 187 514 ± 153 N.S.
MCP-2 (pg/mL) 55 ± 15 47 ± 18 N.S.
MCP-3 (pg/mL) 0 ± 0 0 ± 0 N.S.
MCP-4 (pg/mL) 27 ± 19 30 ± 14 N.S.
MDC (pg/mL) 504 ± 127 463 ± 92 N.S.
MIG (pg/mL) 113 ± 61 119 ± 59 N.S.
MIP-1α (pg/mL) 60 ± 22 43 ± 32 N.S.
MIP-1β (pg/mL) 61 ± 35 69 ± 37 N.S.
MIP-3α (pg/mL) 6 ± 1 7 ± 2 N.S.
MIP-3β (pg/mL) 37 ± 13 56 ± 15 0.00714
MMP-1 (ng/mL) 3.17 ± 2.19 0.68 ± 0.46 0.00612
MMP-10 (pg/mL) 34 ± 45 0 ± 0 N.S.
MMP-13 (pg/mL) 60 ± 114 0 ± 0 N.S.
MMP-2 (ng/mL) 205 ± 35.7 125 ± 31.2 1.09 × 10 -05
MMP-3 (ng/mL) 5.58 ± 2.99 1.44 ± 0.92 5.09 × 10-07
MMP-9 (ng/mL) 48.0 ± 35.6 15.4 ± 9.2 0.00217
MPIF-1 (pg/mL) 599 ± 184 616 ± 199 N.S.
MPO (ng/mL) 45.8 ± 13.6 32.0 ± 6.3 0.00206
NAP-2 (microg/mL) 2.80 ± 2.03 0.21 ± 0.20 8.47 × 10 -05
NT3 (pg/mL) 10 ± 9 5 ± 8 N.S.
OPG (pg/mL) 3 ± 2 7 ± 4 0.00276
OPN (ng/mL) 2.13 ± 1.50 2.91 ± 2.68 N.S.
PAI-1 Active (pg/mL) 211 ± 179 97 ± 93 N.S.
PAI-1 Total (ng/mL) 4.33 ± 2.72 1.67 ± 1.54 0.00585
PDGF-BB (pg/mL) 165 ± 171 85 ± 198 N.S.
RANTES (ng/mL) 10.8 ± 12.2 3.9 ± 1.5 N.S.
SDF-1β (pg/mL) 173 ± 156 237 ± 172 N.S.
TARC (pg/mL) 74 ± 41 39 ± 10 N.S.
TIMP-1 (ng/mL) 121 ± 56.4 82.3 ± 17.1 N.S.
TIMP-2 (ng/mL) 109 ± 25.8 94.0 ± 16.2 N.S.
TNF-α (pg/mL) 46 ± 35 48 ± 38 N.S.
TNF-RI (pg/mL) 433 ± 115 413 ± 111 N.S.
TNF-R2 (pg/mL) 150 ± 46 584 ± 136 6.63 × 10-07
VCAM-1 (ng/mL) 46.5 ± 13.6 69.1 ± 12.0 0.000540
  1. N.S. = Not Significant
  2. *p values were calculated using Student's paired T tests and natural log transformed data.
  3. Values are mean ± one standard deviation.