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Table 1 Genes located in "hot spots" identified by the present meta-analysis

From: Chromosomal imbalances in nasopharyngeal carcinoma: a meta-analysis of comparative genomic hybridization results

Ch Arm Host spot, DSAI Freq (%) Candidate NPC-related Genes references
1 +1q + 1q22-q23.3 25.00 LAMC2 [13]
   + 1q31.1-q32.3 26.06   
2 +2q + 2q31.1-q32.3 17.55   
3 -3p - 3p12.3-p14.1 33.51 FHIT [31]
   - 3p21.2-p21.33 30.32 RASSF1A,, Blu [32,33]
   - 3p24.2-p26.3 29.26 RARβ2, RAF1 [13,34]
  +3q + 3q26.2-q27.2 19.68 deltaN-p63 [35]
6 +6p +6p21.2-p23 23.33 E HSP70-2 [36]
8 +8q + 8q23.1-q24.11 22.87 MYC [37]
9 -9P - 9p21.1-p23 18.61 P14, p16, UBAPI, NGX6 [38–41]
11 +11q + 11q12.3-q13.5 16.49 Cyclin D1 [14]
  -11q - 11q23.1-q25 29.79 TSLC1/IGSF4, [42]
12 +12p + 12p12.1-p12.2 36.17   
   +12p11.21-p11.22 34.04   
  +12q + 12q13.11-q14.1 35.11 MDM2, STAT2 [43,44]
13 -13q - 13q22.1-q31.3 18.61 EDNRB, LIG4 [45,46]
14 -14q - 14q21.1-q21.3 25.00   
   - 14q24.3 27.13 AKTI/PKB, SIVA [43]
15 +15q +15q21.3-q25.3 26.67 E DAPK2 (?) [47]
16 -16q - 16q13-q24.3 29.79 E-cadherin, BRD7 [48,49]
18 +18p +18p 20.00 S   
  +18q +18q21.1-q21.33 21.25 S   
20 +20q +20q11.21-q13.13 30.00 E PLUNC (?) [50]