Figure 4

Highly expressed genes within the Staunton et al Melanoma Component. Gene expression levels of 4 genes within each of the 7 cell lines in the Staunton et al Affymetrix Melanoma Component together with the mean expression levels for the combined non-melanoma cell lines. The expression values were average intensity difference units determined with Affymetrix GENECHIP software that assigned a value of 100 to all expression measurements of less than 100 units. Further details may be found in the Staunton et al publication. The Student t test significance levels for each gene, calculated between the melanoma and the non-melanoma cell lines, were as follows: QPCT (p = .033), MART1 (p = .012), MAGE1 (p = .019) and MAGE3 (p = .024). Note that for clarity of presentation, this figure used expression average intensity difference units, as they were prior to conversion to the standardized z-scores that were used in the PCA and t test calculations.