Figure 6
Average concentration of cytokines/chemokines (pg/ml) in the supernatant of PBMC cultures from 47 donors harvested 24 hours after stimulation with (rIL-2) or without (No Stim) rIL-2 (300 IU/ml). Statistical significance refers to a pair wise t test. Chemokine nomenclature is reported according to the IUIS/WHO subcommittee on chemokine nomenclature [121]. Cytokine/chemokines are displayed in order of significance. In addition to these cytokines/chemokines also IFN-γ (p2-value < 0.01), IFN-α (p2-value = 0.01), lymphotoxin-α (p2-value = 0.02), IL-5 (p2-value = 0.03) and CCL10/IP-10 (p2-value = 0.04) were significantly up-regulated though to a lower degree of significance.