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Table 1 MDA, SOD, GSH-Px concentration and ALT, AST levels in the CHC patients before the treatment and the control group. (Mean ± Standard Deviation)

From: Oxidative stress and antioxidant defense in patients with chronic hepatitis C patients before and after pegylated interferon alfa-2b plus ribavirin therapy

 

Control group (n:28)

CHC Patients (n:19) Before Treatment

P-value

MDA

4,20 ± 1,47

9,28 ± 1,61

<0.001

CuZn-SOD

285,78 ± 96,46

213,84 ± 71,61

<0.05

GSH-Px

8,01 ± 1,79

6,52 ± 1,86

<0.05

ALT

21,53 ± 6,02

95.84 ± 22.68

<0.001

AST

22,50 ± 4,91

80.52 ± 19.27

<0.001

  1. Values are shown as means, p values (<0.05) were derived by the Independent Samples T-test. Units were expressed as follows: MDA as nmol/ml; CuZn-SOD as U/ml,; GSH-Px as U/ml; ALT, AST as U/L.