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Table 1 MDA, SOD, GSH-Px concentration and ALT, AST levels in the CHC patients before the treatment and the control group. (Mean ± Standard Deviation)

From: Oxidative stress and antioxidant defense in patients with chronic hepatitis C patients before and after pegylated interferon alfa-2b plus ribavirin therapy

  Control group (n:28) CHC Patients (n:19) Before Treatment P-value
MDA 4,20 ± 1,47 9,28 ± 1,61 <0.001
CuZn-SOD 285,78 ± 96,46 213,84 ± 71,61 <0.05
GSH-Px 8,01 ± 1,79 6,52 ± 1,86 <0.05
ALT 21,53 ± 6,02 95.84 ± 22.68 <0.001
AST 22,50 ± 4,91 80.52 ± 19.27 <0.001
  1. Values are shown as means, p values (<0.05) were derived by the Independent Samples T-test. Units were expressed as follows: MDA as nmol/ml; CuZn-SOD as U/ml,; GSH-Px as U/ml; ALT, AST as U/L.