Figure 3
From: Induction of antitumor immunity through xenoplacental immunization
Induction of anti-cancer immunity by XPE-pulsed DC. Day 7 bone marrow-derived DC were pulsed with 10 μg/ml XPE for 24 h and injected s.c. (5 × 105 cells/mouse) into syngeneic C57BL/6 mice. A concurrent injection of 5 × 105 B16 melanoma cells was administered. Tumor growth was assessed every 3 days by two measurements of perpendicular diameters by a caliper, and animals were sacrificed when tumors reached a size of 1 cm in any direction. *p < 0.05, Student's T test compared to saline treated.