Table 3 Comparision of glucose usage lactate production and radiation response in the exponentially growing monolayers and as a function of age in spheroids.
Model | Glucose utilization (pico mole/cell/h) | Lactate production (pico mole/cell/h) | Dq(Gy) | D0(Gy) | S.F2 |
|---|---|---|---|---|---|
Monolayer | 0.83 ± 0.03 | 1.47 ± 0.01 | 1.2 | 2.4 | 0.8 ± 0.04 |
7 day spheroid | 2.10 ± 0.07 | 3.67 ± 0.04 | 1.8 | 3.2 | 0.9 ± 0.03 |
28 day spheroid | 1.85 ± 0.05 | 2.93 ± 0.02 | 2.8 | 2.7 | 1.0 ± 0.06 |