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Table 2 Comparison of cell cycle distribution in exponentially growing monolayers and spheroids studied as a function of age.

From: Establishment and characterization of multicellular spheroids from a human glioma cell line; Implications for tumor therapy

Age of spheroids in days

G0/G1

Total S Phase Cells

S-Positive Cells

S-Negative Cells

G2/M

Monolayers

48 ± 3

40 ± 1

40 ± 1

0

12 ± 1

Plateau

72 ± 2

3 ± 2

3 ± 2

0

25 ± 4

07

59 ± 2

20 ± 3

18 ± 3

2 ± 0.5

21 ± 2

14

59 ± 2

20 ± 1

9 ± 1

11 ± 1

21 ± 1

21

56 ± 3

19 ± 2

6 ± 2

13 ± 1

25 ± 3

28

58 ± 4

19 ± 1

5 ± 1

14 ± 1

23 ± 1

  1. Note: All values are mean ± SD of 3 observations from three experiments