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Table 1 T cell subset profile of HIV-1 infected and uninfected infants

From: T lymphocytes among HIV-infected and -uninfected infants: CD4/CD8 ratio as a potential tool in diagnosis of infection in infants under the age of 2 years

 

PCR Positive (n = 76)

PCR Negative (n = 61)

P valuea

Median age (months)

5.5 (IQR: 3–13)

8 (IQR: 4–14)

0.08

Median CD4 + (cells/μL)

521.5 (IQR: 323–805)

1356 (IQR: 916–1769)

<0.001

Median CD8 + (cells/μL)

1302.5 (IQR: 829–2054)

799 (IQR: 471–1020)

<0.001

Median CD4/CD8 ratio

0.4 (IQR: 0.3–0.6)

1.8 (IQR: 1.4–2.3)

<0.001

Median %CD4

13.9 (IQR: 9.2–19.1)

29.9 (IQR: 25.3–34.5)

<0.001

Median %CD8

31.3 (IQR: 22.3–42.9)

18.4 (IQR: 14.2–21.5)

<0.001

  1. Abbreviations: PCR, polymerase chain reaction; n, number tested; P valuea for statistical significance between group medians was estimated using the Kruskal-Wallis test.
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Journal of Translational Medicine

ISSN: 1479-5876

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