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Table 1 T cell subset profile of HIV-1 infected and uninfected infants

From: T lymphocytes among HIV-infected and -uninfected infants: CD4/CD8 ratio as a potential tool in diagnosis of infection in infants under the age of 2 years

  PCR Positive (n = 76) PCR Negative (n = 61) P valuea
Median age (months) 5.5 (IQR: 3–13) 8 (IQR: 4–14) 0.08
Median CD4 + (cells/μL) 521.5 (IQR: 323–805) 1356 (IQR: 916–1769) <0.001
Median CD8 + (cells/μL) 1302.5 (IQR: 829–2054) 799 (IQR: 471–1020) <0.001
Median CD4/CD8 ratio 0.4 (IQR: 0.3–0.6) 1.8 (IQR: 1.4–2.3) <0.001
Median %CD4 13.9 (IQR: 9.2–19.1) 29.9 (IQR: 25.3–34.5) <0.001
Median %CD8 31.3 (IQR: 22.3–42.9) 18.4 (IQR: 14.2–21.5) <0.001
  1. Abbreviations: PCR, polymerase chain reaction; n, number tested; P valuea for statistical significance between group medians was estimated using the Kruskal-Wallis test.