Skip to main content

Table 1 Screening for disorder of haemostasis in the patient with RPL.

From: Acquired factor XII deficiency in a woman with recurrent pregnancy loss: working on a differential diagnosis in a single case

Parameters (unit of measurement)

Results

Normal range

Prothrombin time (INR)

1.15

0.8–1.2

Activated partial thromboplastin time (ratio)

1.45

0.8–1.2

Fibrinogen (mg/dL)

275

220–420

Protein C (%)

93

60–125

Protein S (%)

92

60–125

Antithrombin III (%)

104

80–120

Anticardiolipin Ab IgM (U/GPL)

1.7

< 2.0

Anticardiolipin Ab IgG (U/MPL)

3.9

< 7.0

β-2-GP I Ab

Absent

Absent

Lupus anticoagulant

Absent

Absent

Factor XII (%)

65

80–120

Factor XI (%)

113

80–120

Factor X (%)

112

80–120

Factor IX (%)

99

80–120

Factor VIII (%)

88

65–155

Factor V (%)

110

80–120

MTHFRC677T gene polymorphism

Wild type

Wild type

PTHRA20210 gene polymorphism

Wild Type

Wild type

FVL gene polymorphism

Wild Type

Wild type

  1. INR: international normalised ratio
  2. MTHFRC677T: methylene-tetra-hydrp-folate reductase C677T gene polymorphism
  3. PTHRA20210G: prothrombin A20210G gene polymorphism
  4. FVL: factor V Leiden gene polymorphism
  5. β-2-GP I Ab: Antibodies to β-2-glycoprotein I