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Table 5 Top 31 genes extracted from two different models from PLS-DA SIMCA.

From: Predictors of primary breast cancers responsiveness to preoperative Epirubicin/Cyclophosphamide-based chemotherapy: translation of microarray data into clinically useful predictive signatures

Gene Symbol Gene Description Ref. Sequences Unigene ID
KPNA2 nuclear localization sequence receptor hSRP1alpha, karyopherin alpha 2 (RAG cohort 1 importin alpha 1) NM_002266 4504896
HDAC2 transcriptional regulator homolog RPD3 histone deacetylase 2 similar to yeast RPD3 NM_001527 4557640
PRKAB1 5-AMP-activated protein kinase beta-1, non-catalytic subunit NM_006253 18602783
IMPDH2 inosine monophosphate dehydrogenase (IMPDH2) NM_000884 4504688
YR-29 hypothetical protein clone YR-29 NM_014886 7662676
CD2BP2 CD2 antigen (cytoplasmic tail)-binding protein 2 NM_006110 5174408
FHL2 heart protein (FHL-2) four and a half LIM domains 2 NM_001450 4503722
DDB2 damage-specific DNA binding protein p48 subunit (DDB2; 48 kD) NM_000107 4557514
ASNS asparagine synthetase NM_001673 4502258
XPA XPAC protein xeroderma pigmentosum complementation group A NM_000380 4507936
PLA2G7 LDL-phospholipase A2 phospholipase A2 group VII (platelet-activating factor acetylhydrolase plasma) NM_005084 4826883
BTBD2 BTB (POZ) domain containing 2 hypothetical protein FLJ20386 EST NM_017797 8923361
CCNG1 cyclin G1 clone MGC:6 NM_004060 -
PDHB pyruvate dehydrogenase E1-beta subunit d pyruvate dehydrogenase (lipoamide) beta NM_000925 4505686
MKI67 mki67a (long type)antigen of monoclonal antibody Ki-67 NM_002417 4505188
TNRC15 KIAA0642 protein trinucleotide repeat containing 15 AL_045800 18550089
RPL17 ribosomal protein L17 NM_000985 14591906
GNG12 DKFZp586B0918 (from clone DKFZp586B0918) NM_018841 -
RPL17 ribosomal protein L17 NM_000985 14591906
DKC1 Cbf5p homolog (CBF5) dyskeratosis congenita 1 dyskerin nucleolar protein NM_001363 15011921
DCTN4 dynactin p62 subunit dynactin 4 (p62) NM_016221 14733974
FLJ20273 RNA-binding protein NM_019027 9506670
FLJ11323 hypothetical protein EST NM_018390 8922994
MGC11242 hypothetical protein MGC11242 ESTs NM_024320 13236560
SRR serine racemase Homo sapiens cDNA NM_021947 8922495
ARL3 48c8 ADP-ribosylation factor-like 3 EST NM_004311 4757773
CCNB2 cyclin B2 NM_004701 10938017
MAD2L1 MAD2 protein MAD2 (mitotic arrest deficient yeast homolog)-like 1 NM_002358 6466452
LIG1 membrane glycoprotein LIG-1d NM_015541 18554950
PMSCL1 polymyositisscleroderma autoantigen 1 (75 kD) EST NM_005033 4826921
APBB2 amyloid beta (A4) precursor protein-binding, family B NM_173075 18557629
  1. Note: – Genes in common with EC predictor (Table 3).