Predictors of primary breast cancers responsiveness to preoperative Epirubicin/Cyclophosphamide-based chemotherapy: translation of microarray data into clinically useful predictive signatures

Table 4 Summarized results of validation on the test cohort.

	Predicted response k-NN	Predicted response PLS-DA; model 1	Predicted response PLS-DA; model 2
predicted CR	7	9	10
other	20	18	17
predicted PR	9	4	9
other	18	23	18
predicted NC	11	14	8
other	16	13	19
Sensitivity CR	100	100	100
Specificity CR	87	78	74
PPV	57	44	40
NPV	100	100	100
Sensitivity PR	53	24	35
Specificity PR	100	100	100
PPV	100	100	67
NPV	56	43	39
Sensitivity NC	100	100	50
Specificity NC	76	62	76
PPV	55	43	38
NPV	100	100	84

ISSN: 1479-5876