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Figure 2 | Journal of Translational Medicine

Figure 2

From: Delayed polarization of mononuclear phagocyte transcriptional program by type I interferon isoforms

Figure 2

The genes overexpressed by LPS-stimulated MPs treated by 8 type I IFNs. Unsupervised hierarchical clustering was applied to LPS-stimulated CD14+ MP treated for 9 hours with 42 individual cytokines. FN-β and seven αFNs were clustered into a separate group, the signature IFNs. These IFNs were characterized by the marked overexpression of two groups of genes shown. The genes were overexpressed by the eight IFNs and were identified by visual inspection. The analysis was preformed on the same 2063 genes used in figure 1.

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