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Table 5 Optimal HCV-derived HLA class I restricted CTL epitopes

From: Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "RecycleSpot"

Protein HLA Restriction Sequence Position Reference
Core B60 GQIVGGVYLL 28–37 [67]
Core A0201 YLLPRRGPRL 35–44 [68]
Core B7 GPRLGVRAT 41–49 [69]
Core B44 NEGCGWAGW 88–96 [70]
Core A0201 DLMGYIPLV 132–140 [71]
Core A0201 ALAHGVRAL 150–158 [15]
Core A0201 LLALLSCLTV 178–187 [72]
Core A11 MSTNPKPQK 1–9 [73]
P7 A29 FYGMWPLLL 790–798 [15]
P7 Cw7 FYGMWPLL 790–797 [15]
E1 A0201 ILHTPGCV 220–227 [74]
E1 B35 NASRCWVAM 234–242 [25]
E1 A0201 QLRRHIDLLV 257–266 [74]
E1 A23 FLVGQLFTF 285–293 [15]
E1 A0201 MMMNWSPTT 322–330 [15]
E1 A0201 SMVGNWAKV 363–371 [74]
E1 B35 CPNSSIVY 207–214 [15]
E2 A0201 SLLAPGAKQNV 401–411 [74]
E2 B53 CRPLTDFDQGW 460–469 [69]
E2 B51 YPPKPCGI 489–496 [73]
E2 B60 GENDTDVFVL 530–539 [75]
E2 B50 CVIGGAGNNT 569–578 [73]
E2 A0201 RLWHYPCTV 614–622 [76]
E2 A11 TINYTIFK 621–628 [69]
E2 B60 LEDRDRSEL 654–662 [75]
E2 A2402 EYVLLLFLL 717–725 [77]
E2 B57 NTRPPLGNWF 541–550 [15]
NS2 A29 MALTLSPY 827–834 [25]
NS2 A25 SPYYKRYISW 832–841 [78]
NS2 A23 YISWCLWWL 838–845 [69]
NS3 A24 AYSQQTRGL 1031–1039 [79]
NS3 A0201 CINGVCWTV 1073–1081 [68]
NS3 A0201 LLCPAGHAV 1169–1177 [68]
NS3 A0201 LLCPSGHAV 1169–1177 [68]
NS3 A11 TLGFGAYMSK 1261–1270 [80]
NS3 A0201 ATLGFGAYM 1260–1268 [81]
NS3 A0201 TLHGPTPLL 1617–1625 [81]
NS3 A0201 TGAPVTYSTY 1287–1296 [79]
NS3 A2402 TYSTYGKFL 1292–1300 [77]
NS3 B35 HPNIEEVAL 1359–1367 [82]
NS3 B8 HSKKKCDEL 1395–1403 [69]
NS3 A0201 KLVALGINAV 1406–1415 [68]
NS3 B8 LIRLKPTL 1611–1618 [75]
NS3 A11 TLTHPVTK 1636–1643 [80]
NS3 A68 HAVGLFRAA 1175–1184 [15]
NS3 A0201 GLLGCIITSL 1038–1047 [81]
NS4 A2402 FWAKHMWNF 1760–1768 [77]
NS4 B35 IPDREVLY 1695–1712 [15]
NS4 A24 VIAPAVQTNW 1745–1754 [15]
NS4 B57 LTTSQTLLF 1801–1809 [15]
NS4B A25 EVIAPAVQTNW 1744–1754 [78]
NS4B A25 ETFWAKHMW 1758–1766 [78]
NS4B A0201 SLMAFTAAV 1789–1797 [68]
NS4B A0201 LLFNILGGWV 1807–1816 [72]
NS4B A0201 ILAGYGAGV 1851–1859 [72]
NS4B B37 SECTTPCSGSW 1966–1976 [78]
NS4B B38 AARVTAIL 1941–1948 [75]
NS5 A2 VLSDFKTWL 1987–1995 [83]
NS5 B35 EPEPDVAVL 2162–2170 [15]
NS5 B57 LGVPPLRAWR 2912–2921 [15]
NS5A B60 HEYPVGSQL 2152–2160 [75]
NS5A B35 PCEPEPDVAVL 2161–2171 [75]
NS5A B38 NHDSPDAEL 2218–2226 [75]
NS5A A2 SPDAELIEANL 2221–2231 [75]
NS5A A25 ELIEANLLW 2225–2233 [78]
NS5A A0201 ILDSFDPLV 2252–2260 [68]
NS5A B60 REISVPAEIL 2267–2275 [80]
NS5B A3 SLTPPHSAK 2510–2518 [80]
NS5B A3 RVCEKMALY 2588–2596 [69]
NS5B A2 ALYDWTKL 2594–2602 [78]
NS5B B57 KSKKTPMGF 2629–2637 [80]
NS5B A0201 GLQDCTMLV 2727–2735 [72]
NS5B B38 HDGAGKRVYL 2794–2804 [80]
NS5B A25 TARHTPVNSW 2819–2828 [78]
NS5B A2402 RMILMTHFF 2841–2849 [77]
NS5B A2402 CYSIEPLDL 2870–2878 [77]
NS5B A31 VGIYLLPNR 3003–3011 [80]