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Table 3 Sequence-based typing of NCI-60 HLA class II Loci

From: HLA class I and II genotype of the NCI-60 cell lines

Cell Line ID Tissue DRĪ²1 Locus DQB1 Locus DPB1 Locus
BT-549 41292-D Breast CA 11a, 13a 030101, 060401 020102, 0401
HS 578T 41293-D Breast CA 01a, 150101 050101, 0602 0401, 7801
MCF7 41294-D Breast CA 03a, 15a 0201, 0602 020102, 0401
MDA-MB-231 41296-D Breast CA 0701, 1305 0202, 030101 020102, 1701
MDA-MB435 41297-D Breast CA 040501, 130101 0302, 0603 1301, 1901
T47D 41298-D Breast CA 010201 050101 020102, 0401
SF-268 41286-D CNS CA 03a, 04a 0201, 0302 0401, 0601
SF-295 41287-D CNS CA 14a, 15a 050301, 0602 0401
SF-539 41288-D CNS CA 030101, 12a 0201, 030101 010101, 0401
SNB-19 41289-D CNS CA 030101 0201 0402
SNB-75 41290-D CNS CA 0103, 11a 03a, 050101 0401, 0402
U251 41291-D CNS CA 030101 0201 0402
COLO 205 41299-D Colon CA 040101, 130101 0603 0401
HCC-2998 41300-D Colon CA 11a, 16a 030101, 050201 0401
HCT-116 41301-D Colon CA N.R. 02new, 03new 030101, 0402
HCT-15 41302-D Colon CA 03a, 14a 02a, 050301 010101, 0401
HT29 41303-D Colon CA 0402, 0701 02a, 0302 0401
KM12 41304-D Colon CA 040101 0302 1301
SW-620 41305-D Colon CA 0103, 130101 050101, 0603 010101, 0401
MOLT 4 41281-D Leukemia, ALL 07new, 12new 0202, 030101 20102
CCRF-CEM 41282-D Leukemia, ALL 030101, 0701 0201, 0202 0401, 1301
HL-60 41284-D Leukemia, APL N.R. 030302 0401, 1301
K-562 41280-D Leukemia, CML 03a, 04a 0201, 0302 0401, 0402
SR 41285-D Leukemia, LCIL 01a, 160101 050101, 050201 0401
LOX IMVI 41315-D Melanoma 0701, 150101 0202, 0602 0401, 110101
M 14 41316-D Melanoma 040501, 130101 0302, 0603 1301, 1901
SK-MEL-2 41317-D Melanoma 0402, 130101 030101, 0603 020102, 0401
SK-MEL-5 41319-D Melanoma 040101, 130101 0302, 0603 030101, 1601
SK-MEL-28 41318-D Melanoma 0404 0302 030101
UACC-62 41321-D Melanoma 12a, 130101 030101, 0603 0401, 1401
UACC-257 41320-D Melanoma 040101 030101, 0302 0401
RPMI-8226 41283-D MM 030101, 0701 0201, 0202 010102, 1301
A549/ATCC 41306-D NSCLC 0701, 110401 0202, 030101 N.R.
EKVX 41307-D NSCLC 150101 0602 0401
HOP-62 41308-D NSCLC 13a, 15a 06a, 06a 0402
HOP-92 41309-D NSCLC 01a, 150101 050101, 0602 0401, 0402
NCI-H23 41312-D NSCLC 130101 0603 1901
NCI-H226 41311-D NSCLC 150101, 160101 050201, 0602 020102, 0401
NCI-H322M 41310-D NSCLC 0701 0202 0401
NCI-H460 41313-D NSCLC 01a, 04a 030101, 050101 N.R.
NCI-H522 41314-D NSCLC 040101, 150101 03a, 0602 0401
IGROV1 41322-D Ovarian CA 11a, 11a 03new new, 0501
OVCAR-3 41323-D Ovarian CA 080101, 080401 0402 020102, 0401
OVCAR-4 41324-D Ovarian CA 030101, 040101 0201, 030101 0401, 1301
OVCAR-5 41325-D Ovarian CA 030101, 040101 0201, 030101 0401
OVCAR-8 41326-D Ovarian CA 0701, 150101 030302, 0602 020102, 1301
NCI/ADR-RES 41295-D Ovarian CA 0701, 150101 030302, 0602 020102, 1301
SK-OV-3 41327-D Ovarian CA 01a, 030101 0201, 050101 020102, 0401
DU-145 41328-D Prostate CA N.R. 030302, 050101 0401
PC-3 41329-D Prostate CA 0701, 130101 0202, 0603 0401
786-O 41330-D Renal CA 13a, 15a 06a, 06a 0402
A498 41331-D Renal CA 030101 0201 010101
ACHN 41332-D Renal CA 160101 050201 020102
CAKI-1 41333-D Renal CA 0701, 110401 0202, 03a 020102, 1001
SN12C 41334-D Renal CA 040101, 150101 03a, 0602 N.R.
TK-10 41335-D Renal CA 010201 050101 0402
UO-31 41336-D Renal CA 130201, 150101 0602, 0609 0402, 0501
RXF-393 41337-D Renal CA 110101, 150101 030101, 0602 010101, 0401
  1. Sequence-based typing for the HLA class II loci are reported with the highest degree of resolution. Non-resolved ambiguities are reported as two digit denominations with a superscript a as previously described [43]. HLA typings divergent from those originally described in the ATCC database are reported in red. ID# refers to the HLA laboratory reference number. New alleles are indicated by the suffix new following the allele. N.R. = Ambiguity not resolved at the lower level of resolution.