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Table 1 BRAF mutations and clinical characteristics

From: Clinical significance of BRAF mutations in metastatic melanoma

Clinical Features

BRAF Status

P value

 

Mutation N = 30 (44.1%)

Wild Type N = 38 (55.9%)

 

Gender

   Female

11

15

0.81

   Male

19

23

 

Age 1

   Mean

63.3

57.3

0.12

   Median (range)

56.5 (29–91)

65.0 (42–97)

 

Stage at Diagnosis

   I

5

3

0.92

   II

13

19

 

   III

7

10

 

   IV

4

2

 

   Unknown

1

4

 

Thickness (Number available)

(N = 18)

(N = 22)

 

   Mean

2.98

4.83

0.29

   Median (range)

1.75 (0.2, 20)

2.80 (0.4, 35)

 

Primary Site

   Head/Neck

1

6

 

   Trunk

10

11

 

   Extremities

10

14

 

   Ocular

1

0

 

   Mucosal

1

0

 

   Unknown

7

7

 

Response 2

   CR

2

3

 

   PR

0

2

 

   NR

16

10

 

   Response Rate

11%

33%

0.12

  1. 1 Age at time of biopsy used to assess BRAF sequence.
  2. 2 Response data is based on the 33 patients who received systemic therapy.
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Journal of Translational Medicine

ISSN: 1479-5876

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