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Figure 6 | Journal of Translational Medicine

Figure 6

From: A novel technique for quantifying changes in vascular density, endothelial cell proliferation and protein expression in response to modulators of angiogenesis using the chick chorioallantoic membrane (CAM) assay

Figure 6

LES/ CC5079. (A) p21 was increased in CAM disks treated with systemic CC 5079 as compared to control (P < 0.0001, Student's t test). (B) MetAP-2 trended towards greater expression in CAM disks after systemic CC 5079 injection, but this did not reach statistical significance compared to control (P = 0.0787, Student's t test). (C) CC5079 increased the expression of cleaved caspase-3 (P = 0.0184, Alternate Welch t test) while (D) inhibiting the expression of alpha v beta 3 (P = 0.0266, Alternate Welch t test).

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Journal of Translational Medicine

ISSN: 1479-5876

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