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Table 3 Immune-relevant genes specifically up-regulated by sub-cutaneous melanomas

From: Melanoma-restricted genes

Clone ID

Location

Gene

AVERAGE

t-test (p2-value)

   

SQ

Other

SQ vs Oth

Me vs Oth

295868

1p34

LAPTM5

0.43

-0.68

2.00E-04

3.00E-04

P37265

1p34.3

LCK

0.55

-0.58

1.00E-04

6.00E-06

2563224

1p36.2

PIK3CD

0.8

-0.88

3.00E-07

5.00E-15

842871

1q12

PDE4DIP

0.58

-0.21

5.00E-04

9.00E-05

773509

1q21.3

SNX27

1.05

-0.88

9.00E-11

7.00E-16

701332

1q22

IFI16

0.25

-0.39

2.00E-04

1.00E-05

472009

1q42.1

DISC1

0.35

-0.26

1.00E-07

9.00E-08

746229

2q11.2-q

MAP4K4

0.15

-0.24

7.00E-04

6.00E-05

840466

2q12-q13

MARCO

0.34

-0.28

3.00E-05

2.00E-04

328542

2q24-q3

GALNT3

0.51

-0.4

4.00E-04

1.00E-03

825715

2q37.1

SP110

0.71

-0.59

9.00E-07

3.00E-09

283023

3p21

CX3CR1

0.31

-0.34

2.00E-05

4.00E-10

1605539

4p16.3

IDUA

0.27

-0.29

4.00E-06

6.00E-06

724932

5q35

GRK6

0.43

-0.19

4.00E-05

3.00E-05

753587

6p21.3

BTN3A3

0.49

-0.43

2.00E-05

5.00E-06

753236

6p21.3

TAP2

0.31

-0.42

2.00E-04

1.00E-07

752557

6p21.3

GPSM3

0.42

-0.42

1.00E-04

3.00E-06

2549448

6q21

FYN

0.6

-0.45

1.00E-07

2.00E-07

2306953

8q13.3

LY96

1.01

-0.32

3.00E-06

2.00E-08

645332

10p12

NEBL

0.23

-0.23

6.00E-04

2.00E-04

1631391

11p11.2

BHC80

0.35

-0.29

8.00E-04

4.00E-04

686164

11p11.2

DGKZ

0.44

-0.21

2.00E-04

4.00E-04

487115

11p11.2

PTPRJ

0.78

-0.4

3.00E-09

5.00E-07

151430

11p13

CD44

0.71

-0.22

1.00E-03

2.00E-05

740117

11p15.5

IRF-7

0.53

-0.3

4.00E-05

3.00E-04

P33303

11p15.5

LSP1

0.55

-0.4

1.00E-03

2.00E-05

1850690

11q23.3

BLR1

0.36

-0.36

6.00E-05

2.00E-04

2120815

12p12-p1

KLRG1

0.51

-0.44

1.00E-04

5.00E-04

34637

12p13

CD27

0.72

-0.54

4.00E-04

1.00E-04

1517162

12p13.2-

KLRK1

0.55

-0.53

5.00E-04

6.00E-04

1569551

12q13.11

CSAD

0.37

-0.45

2.00E-04

6.00E-06

429186

13q21.33

LMO7

0.41

-0.37

5.00E-06

4.00E-19

P41256

15q26.3

IL-16

0.64

-0.58

4.00E-05

2.00E-06

P14913

16p11

IL-21R1

0.48

-0.43

6.00E-06

6.00E-04

P07382

16p11.2

ITGAL

0.55

-0.48

2.00E-05

3.00E-06

P12753

16p13.3

NK4;

0.32

-0.3

4.00E-05

3.00E-06

206795

17p

ASGR2

0.57

-0.53

8.00E-05

6.00E-06

488575

17p11.2

ULK2

0.35

-0.17

3.00E-06

1.00E-04

155717

17q23

CD79B

0.44

-0.41

3.00E-05

2.00E-11

156343

17q24.2

MAP3K3

0.62

-0.46

4.00E-06

7.00E-11

P38436

17q25

CARD14

0.54

-0.33

4.00E-08

2.00E-08

1551273

19p12

MEF2B

0.19

-0.21

7.00E-05

1.00E-09

814377

19p13.1

BRD4

0.9

-0.7

6.00E-06

2.00E-16

2010562

19p13.3

MYO1F

0.55

-0.62

9.00E-04

7.00E-05

824384

19p13-q1

CD37

0.64

-0.74

1.00E-03

7.00E-04

788272

19q13.1

CLC

0.61

-0.64

7.00E-06

3.00E-06

815239

19q13.13

ARHGEF1

0.38

-0.42

3.00E-05

1.00E-04

683276

19q13.33

CARD8

0.86

-0.64

1.00E-08

3.00E-05

277906

19q13.4

LILRB1

0.89

-0.51

4.00E-04

5.00E-04

202897

19q13.4

LILRB2

0.72

-0.61

4.00E-04

1.00E-06

2072768

20q12

NCOA3

0.69

-0.36

4.00E-06

2.00E-05

  1. SQ = Average Cy5/Cy3 ratios of10 frozen samples from cutaneous and subcutaneous metastases as described in Table I. Oth = Sample from 80 primary tumors other than melanoma and RCC with the exclusion, in this table of lymph nodal metastases from colorectal cancer (see Table I). Complete and extended gene name is available at http://www.societymelanomaresearch.org
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Journal of Translational Medicine

ISSN: 1479-5876

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