BRCA1-mediated repression of select X chromosome genes

Table 1 X chromosome genes showing two-fold or greater change following BRCA1 expression in HCC1937 BRCA1-null cells.

Name	Clone ID*	Locus	Unigene	Fold repression	Comments
LOC139135	C03503	Xq28	Hs.160594	11.6	Similar to CLOCK protein
EST	32930	Xp11	Hs.99070	8.9
EST	34280	Xp11.2	Hs.99070	8.5
CSTF2	1705354	Xq22.1	Hs.693	5.5
EST	1535341	Xq13	Hs.444962	5.4
EST	1614299	Xq13	Hs.197801	4.3
JM11	1913391	Xp11.23	Hs.417068	3.5
ZNF6	1564783	Xq13	Hs.326801	3.0
ZNF6	5201496	Xq13	Hs.326801	2.4
LOC158572	2070337	Xp11.23	Hs.408191	2.8
LOC158572	1880263	Xp11.2	Hs.408191	2.4
LOC158572	470925	Xp11.23	Hs.408191	2.1
EST	4402168	Xq26	Hs.175894	2.6
KLF8	2148451	Xp11.21	Hs.411296	2.5
KLF8	2148451	Xp11.21	Hs.411296	2.3
EST	2516780	Xp11.23	Hs.293317	2.4	Moderately similar to PAGE-5 protein
EST	2659258	Xq28	Hs.312560	2.2
ED1	2030638	Xq12-q13	Hs.105407	2.2	Weakly similar to PAGE-5 protein
TIMP1	172210	Xp11.23	Hs.446641	2.1
EST	2111889	Xp11.23	Hs.163473	2.0	Weakly similar to XAGE-5 protein
FLJ23614	1938584	Xq26	Hs.28780	1.9

*I ntegrated M olecular A nalysis of G enomes and their E xpression (I.M.A.G.E.) Consortium cDNA clone identification.

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