Table 2 Biological characteristics of dendritic cells used for vaccination
From: Evaluation of in vivo labelled dendritic cell migration in cancer patients
iDC median % (range) | mDC median % (range) | |
|---|---|---|
DC surface markers: | ||
CD 1a | 20 (4–58) | 2 (0–8) |
CD 14 | 3 (0–7) | 2 (0–11) |
CD 80 | 3 (1–23) | 37 (27–87) |
CD 86 | 30 (10–55) | 81 (15–94) |
HLA-DR | 45 (17–82) | 78 (56–88) |
CD 83 | 2 (0–13) | 55 (34–73) |
CCR7 | 4 (2–5) | 86 (48–92) |
Endocytosis % of positive cells | 70 (39–91) | 15 (1–42) |
IL-12 production pg/ml | 49 (17–225) | > 1350 |
IL-10 production pg/ml | 0 | 0 |
% purity * | 74 (66–98) | 59 (31–100) |
% vitality ** | 75 (68–79) | 82 (66–89) |