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Table 2 Biological characteristics of dendritic cells used for vaccination

From: Evaluation of in vivo labelled dendritic cell migration in cancer patients

  iDC median % (range) mDC median % (range)
DC surface markers:   
   CD 1a 20 (4–58) 2 (0–8)
   CD 14 3 (0–7) 2 (0–11)
   CD 80 3 (1–23) 37 (27–87)
   CD 86 30 (10–55) 81 (15–94)
   HLA-DR 45 (17–82) 78 (56–88)
   CD 83 2 (0–13) 55 (34–73)
   CCR7 4 (2–5) 86 (48–92)
Endocytosis % of positive cells 70 (39–91) 15 (1–42)
IL-12 production pg/ml 49 (17–225) > 1350
IL-10 production pg/ml 0 0
% purity * 74 (66–98) 59 (31–100)
% vitality ** 75 (68–79) 82 (66–89)
  1. * viable DC/viable DC + viable lymphocytes ** viable DC + viable lymphocytes/total cells