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Table 1 Data sources used to explore the different biomedical dimensions of the project and for validation purposes.

From: Synergy-COPD: a systems approach for understanding and managing chronic diseases

Data-sets

Data-types

Reference

Brief Description.

BioBridge

Metabolomics, Proteomics, Transcriptomics, Physiological and Clinical Measurements

[27], [83], [84],

COPD patients with low and normal fat free mass index and healthy subjects studied before and after training.

PAC-COPD

Clinical Measurements and Co-morbidity data.

[75]

COPD patients studied after the first hospitalization because of an episode of exacerbation.

Medicare

ICD9 codes from hospital registries.

[85], [85]

Health Insurance Program

Animal experiments

Muscle Transcriptomics and muscle & blood Cytokines. Role of eiF6 in energy metabolism

Synergy-COPD-FP7-ICT-270086:2010-13.

Guinea Pig and mice models, C2C12 cell culture. Normoxic and hypoxic conditions

Public datasets

SNOMED-CT, MeSH, angiogenesis-related expression data, etc.

See Table 1 in COPDKB [35]

Public resources integrated into the Synergy-COPD Knowledge Base.