Global distribution of polymorphisms (Pol) | Response N (%) | Stabilization or progression N (%) | p value |
---|---|---|---|
VNTR | |||
2R/2R | 7 (77.8) | 2 (22.2) | 0.055 |
3R/3R | 7 (100) | 0 (0) | |
2R/3R | 4 (50) | 4 (50) | |
3R/4R | 0 (0) | 1 (100) | |
Pol VNTR (Subanalysis by EGFR status; group of native EGFR-patients) | |||
2R/2R | 7 (77.8) | 2 (22.2) | 0.017 |
3R/3R | 7 (100) | 0 (0) | |
2R/3R | 2 (33.3) | 4 (66.7) | |
3R/4R | 0 (0) | 1 (100) | |
Global distribution of SNP | |||
Absence | 6 (85.7) | 1 (14.3) | 0.626 |
Presence | 12 (66.7) | 6 (33.3) | |
Global distribution of polymorphisms in 3′-UTR | |||
+6/+6 | 10 (83.3) | 2 (16.7) | 0.234 |
+6/-6 | 6 (54.5) | 5 (45.5) | |
-6/-6 | 2 (100) | 0 (0) | |
Pol 3′-UTR (Subanalysis by smoking habit stratification; group of active and former smokers) | |||
+6/+6 | 8 (100) | 0 (0) | 0.085 |
+6/-6 | 4 (50) | 4 (50) | |
-6/-6 | 2 (100) | 0 (0) |