Comparative expression profiles of microRNA in left and right atrial appendages from patients with rheumatic mitral valve disease exhibiting sinus rhythm or atrial fibrillation

Table 3 miRNA expression differences between AF-LAA and SR-LAA

miRNA	SR-LAA signal	AF-LAA signal	Log₂ ^{(AF-LAA/SR-LAA)}	P-value
Up-regulated (n = 22*)
hsa-miR-3613-3p	294	3063	3.38	1.07E-02
hsa-miR-494	296	1881	2.67	5.89E-02
hsa-miR-3591-3p	539	2069	1.94	7.14E-02
hsa-miR-4485	80	284	1.83	5.03E-02
hsa-miR-574-3p	4478	13516	1.59	2.41E-02
hsa-miR-466	1183	3343	1.50	2.31E-02
hsa-miR-4492	334	834	1.32	2.73E-02
hsa-let-7d-3p	146	344	1.23	9.94E-02
hsa-miR-4707-5p	387	857	1.15	2.92E-02
hsa-miR-4534	79	172	1.12	6.66E-02
hsa-miR-3940-5p	397	803	1.02	5.71E-02
hsa-miR-3178	185	374	1.01	1.97E-02
hsa-miR-15b-5p	383	723	0.92	3.04E-02
hsa-miR-21-5p	442	819	0.89	4.66E-02
hsa-miR-3196	1383	2477	0.84	1.34E-02
hsa-miR-1307-3p	82	145	0.83	5.28E-02
hsa-miR-331-3p	140	247	0.82	6.46E-02
hsa-miR-149-3p	96	163	0.77	6.79E-02
hsa-miR-181a-5p	1057	1613	0.61	8.50E-02
hsa-miR-30a-5p	249	376	0.59	6.94E-02
hsa-miR-1973	745	1123	0.59	6.02E-02
hsa-miR-4497	4574	6546	0.52	4.68E-02
Down-regulated (n = 20*)
hsa-miR-1	12740	3079	−2.05	1.94E-02
hsa-miR-26b-5p	794	198	−2.00	2.30E-02
hsa-miR-4454	1262	488	−1.37	3.93E-02
hsa-miR-361-5p	652	259	−1.33	3.53E-02
hsa-miR-151a-5p	694	302	−1.20	3.90E-02
hsa-miR-26a-5p	9702	4314	−1.17	7.22E-03
hsa-miR-378a-3p	683	307	−1.15	7.26E-02
hsa-miR-5190	311	141	−1.14	9.06E-02
hsa-miR-5100	775	363	−1.10	2.89E-02
hsa-miR-151b	609	288	−1.08	6.25E-02
hsa-miR-4442	350	169	−1.05	6.69E-02
hsa-miR-2861	2103	1141	−0.88	6.50E-02
hsa-miR-143-3p	1380	778	−0.83	9.49E-02
hsa-miR-378d	197	112	−0.82	7.07E-02
hsa-miR-23c	939	583	−0.69	8.28E-02
hsa-miR-195-5p	612	385	−0.67	2.21E-02
hsa-miR-720	952	619	−0.62	4.67E-02
hsa-miR-4281	836	545	−0.62	6.92E-02
hsa-let-7f-5p	10225	7040	−0.54	5.58E-02
hsa-miR-23b-3p	12468	8685	−0.52	7.24E-02

*Expression levels of miRNAs are described as up-regulated or down-regulated in AF-LAA relative to those in SR-LAA.

ISSN: 1479-5876