Detectability based on percent of samples > LLOQ | Detected in less than 50% of samples for all three sample types | CCL3, CSF2, FABP3, HSPD1, IL10, IL12A/IL12B, IL17A, IL1B, IL2, IL23B, IL3, IL4, IL5, IL6, IL7, INS_intact, INS_total, LTA, MDA-LDL, MICA, NGF, S100B, TNF |
Detected in >50% of serum samples but not in > 50% of EDTA or P100 plasma samples | IL1A, IL1RN, IL12B, OLR1 | |
Detected in >50% of EDTA and P100 plasma samples but not in > 50% of serum samples | FGA_FGB_FGG, IFNG, MMP2 | |
Measurability based on reliability and CV | Reliability values <0.60 or CV (%) ≥ 20 in all three sample types in samples where one or more sample types had >50% of samples > LLOQ. | ALB, CA9, IFNG, IL1RN, IL12B, SPINK1, TIMP1 |
Performed better* in EDTA plasma compared to serum | ADIPOQ, AGER, ALB$, CCL16, CCL5, CRP, GC, HP, IgM, MMP9, SERPINE1, VEGFA | |
Perform better & in serum compared to EDTA plasma | ANGPT1, CA9$, CEACAM1, CCL2, CCL20, FAS, HGF, IL18, KITLG, SERPINA3, THBD | |
Ratio of CV of P100:EDTA plasma > 1.5 | ADIPOQ, CXCL9, IL18BP, IgM, PEACAM1, SPINK1$, SFTPD, VEGFA | |
Ratio of CV of P100:EDTA plasma < 0.667 | CCL4 | |
Measured values | Mean levels > 1.5 fold higher in serum compared to plasma | A2M, ANGPT1, BDNF, CCL11, CCL13, CCL2, CCL24, CCL5, HGF, MMP3, LTF, SERPINE1, SFTPD, TGFB1_LAP, TIMP1$, TNFRSF11B, VEGFA |
Mean levels > 1.5 fold higher in plasma compared to serum | CDH13, MMP9, SOD1 |