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Table 1 In vivo heart functional parameters of rats by ECG at 4 weeks

From: Up-regulation of heme oxygenase-1 after infarct initiation reduces mortality, infarct size and left ventricular remodeling: experimental evidence and proof of concept

 

Sham group

MI group

CoPP-MI group

CoPP + SnMP -MI group

n = 20

n = 35

n = 25

n = 6

ÂQRS (cases >90°)

59° ± 2 (0/20)

128° ± 2**# (35/35)

94° ± 5** (12/25)

125° ± 7**# (6/6)

IQRS (mV)

4.1 ± 0.2

2.6 ± 0.1**#

3.6 ± 0.2

2.4 ± 0.2**#

TQRS (ms)

14 ± 0.6

19 ± 0.5**#

15 ± 0.5

18 ± 1.6**#

  1. Values are mean ± SEM; n, number of animals tested; ÂQRS, frontal QRS axis; IQRS, QRS amplitude index; TQRS, QRS duration; **p < 0.001 vs sham-operated; #p < 0.001 vs. CoPP-treated infarct.