Table 2 Multivariable analysis of CD8 and CD45RO with pT. pN, cM, and postoperative therapy
CD8i | CD8s | CD45ROi | CD45ROs | ||||||
|---|---|---|---|---|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | ||
Marker | Low | 1.0 | 0.0038 | 1.0 | 0.0049 | 1.0 | 0.2644 | 1.0 | 0.0213 |
High | 0.55 (0.36-0.82) | 0.72 (0.57-0.9) | 0.88 (0.71-1.1) | 0.76 (0.61-0.96) | |||||
pT | pT1-2 | 1.0 | 0.9525 | 1.0 | 0.4854 | 1.0 | 0.3584 | 1.0 | 0.4897 |
pT3-4 | 1.03 (0.39-2.75) | 1.41 (0.54-3.67) | 1.59 (0.6-4.3) | 1.41 (0.53-3.72) | |||||
pN | pN0 | 1.0 | 0.6523 | 1.0 | 0.7057 | 1.0 | 0.6596 | 1.0 | 0.3729 |
pN1-2 | 0.82 (0.36-1.9) | 0.85 (0.37-1.95) | 0.83 (0.36-1.9) | 0.69 (0.3-1.6) | |||||
cM | cM0 | 1.0 | 0.0683 | 1.0 | 0.0485 | 1.0 | 0.1844 | 1.0 | 0.1348 |
cM1 | 2.05 (0.95-4.4) | 2.2 (1.01-4.81) | 1.7 (0.78-3.7) | 1.8 (0.83-3.9) | |||||
Postoperative therapy | None | 1.0 | 0.2672 | 1.0 | 0.2425 | 1.0 | 0.3805 | 1.0 | 0.4301 |
Yes | 0.63 (0.28-1.42) | 0.63 (0.29-1.37) | 0.7 (0.32-1.55) | 0.73 (0.33-1.6) |