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Figure 2 | Journal of Translational Medicine

Figure 2

From: CD8/CD45RO T-cell infiltration in endoscopic biopsies of colorectal cancer predicts nodal metastasis and survival

Figure 2

Prognostic effects of CD8 and CD45RO T-cell infiltration in the pre-operative biopsy. A, B: Strong infiltration by CD8 cells in the pre-operative biopsy predicted a significantly prolonged survival independent of stromal or intraepithelial location (CD8i: p = 0.0026; 75th-percentile as cut-off, >6.2 cells; CD8s: p = 0.0011; 50th percentile as cut-off, >37.6 cells). C, D: Patients with strong CD45ROs infiltration derived a significant survival benefit (CD45ROs: p = 0.0031; 50th-percentile as cut-off, >56.6 cells). No significant associations with survival time were observed for CD45ROi infiltrates (CD45ROi; p = 0.0941; 50th percentile as cut-off, > 3.4 cells).

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