Table 2 Gene expression of cathepsin K, CD3, CD14 and of cytokines in tissue of patients with metallosis
From: On the inflammatory response in metal-on-metal implants
Parameter | Cup | Muscle | Difference between groups calculated by Mann–Whitney test |
|---|---|---|---|
Cathepsin K | 2603.0 ± 1220.8* | 968.4 ± 392.4 | n.d. |
CD3 | 288.6 ± 262.2 | 42.2 ± 26.4 | p = 0.036 |
CD14 | 1806.2 ± 1211.9 | 334.2 ± 247.7 | p = 0.012 |
CXCL8 | 677.0 ± 355.5 | 27.0 ± 20.8 | p = 0.043 |
IL1ß | 101.4 ± 90.7 | 9.0 ± 3.5 | p = 0.043 |
CXCL2 | 276.5 ± 125.0 | 92.8 ± 51.5 | p = 0.040 |
MRP14 | 82376.8 ± 78340.0 | 377.4 ± 396.0 | p = 0.040 |
RANK | 10.9 ± 9.8 | 8.2 ± 5.7 | n.d. |
RANKL | 4.1 ± 4.0 | 0.2 ± 0.2 | n.d. |
TNFα | 11.5 ± 4.0 | 7.3 ± 1.0 | n.d. |
CXCL10 | 184.7 ± 239.5 | 131.6 ± 147.8 | n.d. |
CCL2 | 1612.1 ± 1958.9 | 652.0 ± 144.8 | n.d. |