Figure 7
From: Regulatory mechanisms of betacellulin in CXCL8 production from lung cancer cells
The percentage of lung cancer cells (A549 cells) movement was assessed using Cell-IQ Alive Image Monitoring System, at 72 h. The percentage of A549 cells movement significantly increased (∎) after the stimulation with BTC, compared to the average of total cells values treated with vehicle (DMSO) alone (●), while cells treated with BEZ235 (A), GDC0941 (B), SHBM1009 (C), Erlotinib (D) or PD98059 (E) showed a lower increase, or even a decrease in the percentage of A549 cells movement, at doses of 0.1, 1 or 10 μM, respectively. Data were presented as mean ± SEM and each group has 6–12 measurements.