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Figure 6 | Journal of Translational Medicine

Figure 6

From: Regulatory mechanisms of betacellulin in CXCL8 production from lung cancer cells

Figure 6

The percentage of the differentiated lung cancer cells (A549 cells) was assessed using Cell-IQ Alive Image Monitoring System, at 72 h. The percentage of differentiated cells significantly increased () after the stimulation with BTC, compared to the average of total cells values treated with vehicle (DMSO) alone (), while cells treated with BEZ235 (A), GDC0941 (B), SHBM1009 (C), Erlotinib (D) or PD98059 (E) showed a lower increase, or even a decrease in the percentage of differentiated cells, at doses of 0.1, 1 or 10 μM, respectively. Data were presented as mean ± SEM and each group has 6–12 measurements.

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