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Table 2 Correlation of peritumoral CD66+ neutrophils, CD8+ lymphocytes and NLR with clinicopathological parameters

From: The clinical significance of tumor-infiltrating neutrophils and neutrophil-to-CD8+ lymphocyte ratio in patients with resectable esophageal squamous cell carcinoma

  Total Peritumoral neutrophilsa Peritumoral CD8+ lymphocytesa Peritumoral NLR
90 Low High P value Low High P value <l ≥1 P value
Gender           
Male 72 38 34 0.292 37 35 0.598 40 32 0.009
Female 18 7 11   8 10   16 2  
Age 42-78          
<60.5b 45 25 20 0.292 25 20 0.292 27 18 0.664
≥60.5 45 20 25   20 25   29 16  
Tumor location           
Upper 10 6 4 0.612 6 4 0.769 6 4 0.634
Middle 48 25 23   24 24   28 20  
Lower 32 14 18   15 17   22 10  
Tumor length 0.5-8.5          
<4.0b 52 18 26 0.092 20 24 0.399 30 14 0.254
≥4.0 38 27 19   25 21   26 20  
Differential grade           
Well 25 9 16 0.185 14 11 0.764 12 13 0.221
Middle 39 20 19   19 20   26 13  
Poor 26 16 10   12 14   18 8  
T stage           
1 and 2 31 18 13 0.267 12 19 0.12 27 4 <0.001
3 and 4 59 27 32   33 26   29 30  
LN metastasis           
Negative 57 27 30 0.512 26 31 0.274 40 17 0.041
Positive 33 18 15   19 14   16 17  
Positive LN           
0 57 27 30 0.764 26 31 0.045 40 17 0.014
1 12 7 5   10 2   3 9  
≥2 21 11 10   9 12   13 8  
pTNM stage           
I 18 9 9 0.972 8 10 0.536 13 5 0.053
II 41 21 20   19 22   29 12  
III 31 15 16   18 13   14 17  
Recurrence           
Yes 63 31 32 0.818 32 31 0.818 38 25 0.569
No 27 14 13   13 14   18 9  
  1. LN lymph node, pTNM pathological tumor node metastasis, NLR CD66+ neutrophil-to-CD8+ lymphocyte ratio, values in bold signify p < 0.05, aGrouped by median, bThe median.