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Table 1 Correlation of intratumoral CD66+ neutrophils, CD8+ lymphocytes and NLR with clinicopathological parameters

From: The clinical significance of tumor-infiltrating neutrophils and neutrophil-to-CD8+ lymphocyte ratio in patients with resectable esophageal squamous cell carcinoma

 

Total

Intratumoral neutrophilsa

Intratumoral CD8+ lymphocytesa

Intratumoral NLR

90

Low

High

P value

Low

High

P value

<l

≥1

P value

Gender

          

Male

72

34

38

0.292

36

36

1.0

39

33

0.46

Female

18

11

7

 

9

9

 

8

10

 

Age

42-78

         

<60.5b

45

25

20

0.292

28

17

0.02

21

24

0.291

≥60.5

45

20

25

 

17

28

 

26

19

 

Tumor location

          

Upper

10

5

5

1.0

6

4

0.438

6

4

0.858

Middle

48

24

24

 

21

27

 

25

23

 

Lower

32

16

16

 

18

14

 

16

16

 

Tumor length

0.5-8.5

         

<4b

52

21

23

0.673

21

23

0.673

20

24

0.209

≥4

38

24

22

 

24

22

 

27

19

 

Differential Grade

          

Well

25

14

11

0.764

11

14

0.744

12

13

0.777

Middle

39

19

20

 

21

18

 

22

17

 

Poor

26

12

14

 

13

13

 

13

13

 

T stage

          

1 and 2

31

18

13

0.267

15

16

0.824

17

14

0.719

3 and 4

59

27

32

 

30

29

 

30

29

 

LN metastasis

          

Negative

57

34

23

0.016

29

28

0.827

30

27

0.919

Positive

33

11

22

 

16

17

 

17

16

 

Positive LN

          

0

57

34

23

0.055

29

28

0.968

30

27

0.835

1

12

4

8

 

6

6

 

7

5

 

≥2

21

7

14

 

10

11

 

10

11

 

pTNM stage

          

I

18

12

6

0.013

8

10

0.87

12

6

0.343

II

41

24

17

 

21

20

 

21

20

 

III

31

9

22

 

16

15

 

14

17

 

Recurrence

          

Yes

63

24

39

0.001

32

31

0.818

31

32

0.382

No

27

21

6

 

13

14

 

16

11

 
  1. LN lymph node, pTNM pathological tumor node metastasis, NLR, CD66+ neutrophil-to-CD8+ lymphocyte ratio, values in bold signify p < 0.05, aGrouped by median, bThe median.