Skip to main content

Advertisement

Table 1 Correlation of intratumoral CD66+ neutrophils, CD8+ lymphocytes and NLR with clinicopathological parameters

From: The clinical significance of tumor-infiltrating neutrophils and neutrophil-to-CD8+ lymphocyte ratio in patients with resectable esophageal squamous cell carcinoma

  Total Intratumoral neutrophilsa Intratumoral CD8+ lymphocytesa Intratumoral NLR
90 Low High P value Low High P value <l ≥1 P value
Gender           
Male 72 34 38 0.292 36 36 1.0 39 33 0.46
Female 18 11 7   9 9   8 10  
Age 42-78          
<60.5b 45 25 20 0.292 28 17 0.02 21 24 0.291
≥60.5 45 20 25   17 28   26 19  
Tumor location           
Upper 10 5 5 1.0 6 4 0.438 6 4 0.858
Middle 48 24 24   21 27   25 23  
Lower 32 16 16   18 14   16 16  
Tumor length 0.5-8.5          
<4b 52 21 23 0.673 21 23 0.673 20 24 0.209
≥4 38 24 22   24 22   27 19  
Differential Grade           
Well 25 14 11 0.764 11 14 0.744 12 13 0.777
Middle 39 19 20   21 18   22 17  
Poor 26 12 14   13 13   13 13  
T stage           
1 and 2 31 18 13 0.267 15 16 0.824 17 14 0.719
3 and 4 59 27 32   30 29   30 29  
LN metastasis           
Negative 57 34 23 0.016 29 28 0.827 30 27 0.919
Positive 33 11 22   16 17   17 16  
Positive LN           
0 57 34 23 0.055 29 28 0.968 30 27 0.835
1 12 4 8   6 6   7 5  
≥2 21 7 14   10 11   10 11  
pTNM stage           
I 18 12 6 0.013 8 10 0.87 12 6 0.343
II 41 24 17   21 20   21 20  
III 31 9 22   16 15   14 17  
Recurrence           
Yes 63 24 39 0.001 32 31 0.818 31 32 0.382
No 27 21 6   13 14   16 11  
  1. LN lymph node, pTNM pathological tumor node metastasis, NLR, CD66+ neutrophil-to-CD8+ lymphocyte ratio, values in bold signify p < 0.05, aGrouped by median, bThe median.