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Table 1 Demographic and clinical characteristics at the time of study of SLE and healthy controls

From: IL-37 inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells of patients with systemic lupus erythematosus: its correlation with disease activity

Characteristics

SLE patients (n = 66)

Healthy controls (n = 41)

Age (years)

30.5 ± 8.02 (18-54)

31.8 ± 9.57 (19-58)

Sex (female/male)

59/7

37/4

Disease duration (years)

2.0 ± 1.12

-

Arthritis n (%)

3 (4.5)

-

Renal diseases n (%)

40 (60.6)

-

Fever n (%)

13 (19.7)

-

Neurological disorder n (%)

1 (1.5)

-

Leukopenia n (%)

11 (16.7)

-

Thrombocytopenia n (%)

8 (12.1)

-

Anti-ds-DNA antibody n (%)

39 (59.1)

-

Anti-Smith antibody n (%)

30 (45.5)

-

Anti-AnuA antibody n (%)

20 (30.3)

-

Anti-rRNP antibody n (%)

11 (16.7)

-

ESR

29.2 ± 27.80

-

Low C3 n (%)

33 (50.0)

-

Low C4 n (%)

29 (43.9)

-

IgG (g/L)

16.2 ± 5.63

-

IgM (g/L)

1.21 ± 0.64

-

IgA (g/L)

2.33 ± 1.09

-

SLEDAI

(2-14) 6.34 ± 3.26

-

  1. Except where otherwise indicated, values are expressed as mean ± standard deviation. There were no significant differences between patients with SLE and healthy donors in terms of age and sex. Anti-ds-DNA antibody, anti-double stranded DNA antibody; Anti-Smith antibody, anti-smith-antibody; Anti-AnuA antibody, anti-nucleosome antibody; Anti-rRNP antibody, Anti-Ribosomal RNP Antibody; ESR, erythrocyte sedimentation rate; C3, complement 3; C4, complement 4; IgG, Immunoglobulin G; IgM, Immunoglobulin M; IgA, Immunoglobulin A; SLE, systemic lupus erythematosus; SLEDAI, SLE disease activity index.