Skip to main content

Advertisement

Figure 2 | Journal of Translational Medicine

Figure 2

From: IL-37 inhibits the production of inflammatory cytokines in peripheral blood mononuclear cells of patients with systemic lupus erythematosus: its correlation with disease activity

Figure 2

Comparison of IL-37 mRNAs and protein levels among SLE patients with active disease and inactive disease as well as HC. (A) Levels of IL-37 mRNAs in PBMCs from SLE patients, distributed according to disease activity (i.e. active (n = 36) versus inactive (n = 30)), were compared by RT-PCR with those from healthy controls (HC, n = 41). Results are depicted as box plots, with median values, 25th and 75th quartile and the range of values. (B) Serum IL-37 protein levels in SLE patients, distributed according to disease activity (i.e. active (n = 36) versus inactive (n = 30)), were compared by ELISA with those from healthy controls (HC, n = 41). Each symbol represents an individual patient. Horizontal lines indicate median values. Mann-Whitney U-test and associated P values are indicated. NS, no significant.

Back to article page