Epitope peptides
|
Sequence
|
Binding score* to HLA-A*24:02
|
Expression in colorectal cancer (%)
|
Remarks on function and tumor relevance
|
References
|
---|
RNF43 - 721
|
NSQPVWLCL
|
10
|
90%
|
Growth of cancer cells
|
[4, 17]
|
TOMM34 - 299
|
KLRQEVKQNL
|
13.4
|
80%
|
Growth of cancer cells
|
[5]
|
KOC1 - 508
|
KTVNELQNL
|
14.4
|
77%
|
Metastasis and invasion
|
[6, 7, 18]
|
VEGFR1 - 1084
|
SYGVLLWEI
|
66
|
100%**
|
Tumor angiogenesis,growth through autocrine
|
[14, 15, 19, 20]
|
VEGFR2 - 169
|
RFVPDGNRI
|
22
|
- *The binding affinities were estimated using the BioInformatics and Molecular Analysis Section websites.
- **100% in tumor cells as well as tumor associated neovascularity.