From: Proteomic profiling of lymphocytes in autoimmunity, inflammation and cancer
Identified proteins | Expression | Number of peptides | Function |
---|---|---|---|
Integrin β | Up-regulated | Singe | Protein binding |
Coronin-2A | Up-regulated | Singe | Protein binding |
C19orf2 protein | Up-regulated | Singe | Protein binding |
Isoform 4 of Dystrophin | Up-regulated | Singe | Structural constitute of cytoskeleton, muscle; protein, calcium ion, actin, zinc ion binding |
Synaptonemal complex protein 2 | Up-regulated | Singe | DNA binding |
Hypothetical protein LOC345651 | Up-regulated | Singe | Protein binding |
Isoform 1 of Solute carrier family 22 member 11 | Up-regulated | Singe | Sodium-independent organic anion transporter activity |
UBC; UBB ubiquitin and ribosomal protein S27a precursor | Up-regulated | Singe | Structural constituent of ribosome |
PRA1 family protein 3 | Up-regulated | Singe | Protein binding |
Actin, cytoplasmic 1 | Up-regulated | Singe | Structural constituent of cytoskeleton; protein, ATP, nucleotide binding |
Probable G-protein coupled receptor 179 precursor | Up-regulated | Singe | Metabotropic glutamate, GABA-B-like receptor activity |
Heat shock 70Â kDa protein 9, mitochondrial precursor | Up-regulated | Singe | Unfolded protein binding; ATP, nucleotide binding |
ELMO2 protein | Up-regulated | Singe | Binding |
Isoform 1 of Peripherin | Down-regulated | Singe | Structural molecule activity |
ATP synthase subunit α, mitochondrial precursor | Down-regulated | Singe | Protein, ATP, nucleotide, metal ion binding; hydrogen-transporting ATPase/ATP synthase activity; hydrolase, transporter activity |
Calnexin precursor | Down-regulated | Singe | Calcium ion, sugar binding; unfolded protein binding |
Integrin β-2 precursor | Down-regulated | Singe | Protein, protein kinase binding; receptor activity |
Vimentin | Up-regulated | Two or more | Structural constituent of cytoskeleton; protein binding; structural molecule activity; oxygen transporter activity |
Keratin, type I cytoskeletal 10 | Up-regulated | Two or more | Structural constituent of epidermis; structural molecule activity |
ATP synthase subunit β, mitochondrial precursor | Up-regulated | Two or more | Protein, ATP, nucleotide, metal ion binding; hydrogen-transporting ATPase/ATP synthase activity; hydrolase, transporter activity; hydrogen-exporting ATPase activity; nucleotide-triphosphatase activity |
Actin, aortic smooth muscle | Up-regulated | Two or more | Structural constituent of cytoskeleton; protein, ATP, nucleotide binding |
Keratin, type II cytoskeletal 1 | Up-regulated | Two or more | Structural constituent of cytoskeleton; protein, sugar binding; receptor activity |
Uncharacterized protein ALB | Up-regulated | Two or more | Protein, water, toxin, pyridoxal phosphate, drug, fatty acid, oxygen, copper ion, DNA, metal ion binding; carrier, antioxidant activity |
Isoform ASF-1 of Splicing factor, arginine/serine-rich 1 | Down-regulated | Two or more | Protein, nucleotide, RNA binding |