Figure 2

Inflammation in the peripheral blood and kidney. The serum level of TNF-α (A) and IFN-γ (B) showed a stable increase after transplantation, a summit at day 5 and a gradual decrease thereafter. Immunohistochemistry staining at 400× magnification displayed that MPO + cells scattered in the posttransplant kidneys, mostly in vascular lumens and interstitial areas and some also in glomerular areas, or penetrating through tubular areas (C). The number of MPO + cells markedly increased from day 2, culminated at day 5 and notably reduced since day 7 till day 14 (D). Data are expressed as mean ± SEM (n = 3). Post N: post nephrectomy. *: P < 0.05; **: P < 0.01; ***: P < 0.001.